CIDEA
Reaktivität: Human
ELISA
Wirt: Kaninchen
Polyclonal
HRP
Applikationshinweise
ELISA. Western Blot: CIDE-A antibody can be used for detection of CIDE-A at 1/1000 to 1/2000dilution. An approximately 23 kDa band can be detected. Immunohistochemistry. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C.
Target
CIDEA
(Cell Death-Inducing DFFA-Like Effector A (CIDEA))
CIDE-A antikoerper, AW212747 antikoerper, CIDEA antikoerper, cide-a antikoerper, MGC89985 antikoerper, cell death-inducing DFFA-like effector a antikoerper, cell death-inducing DNA fragmentation factor, alpha subunit-like effector A antikoerper, cell death-inducing DFFA-like effector a L homeolog antikoerper, CIDEA antikoerper, Cidea antikoerper, cidea antikoerper, cidea.L antikoerper
Hintergrund
Apoptosis is related to many diseases and induced by a family of cell death receptors. Cell death signals are transduced by DD-, DED-, or CARD-containing molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase DFF40/CAD, which is chaperoned and inhibited by DFF45/ICAD (1-4). DFF45 related proteins CIDE-A and CIDE-B (for cell death-inducing DFF-like effector A and B) were recently identified (5). CIDE contains a new type of domain termed CIDE-N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD (5,6). Expression of CIDE-A induces DNA fragmentation and activates apoptosis, which is inhibited by DFF45. CIDE-A is expressed in many tissues.Synonyms: CIDE A, CIDEA, Cell death activator CIDE-A, Cell death-inducing DFFA-like effector A