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ALOXE3 Antikörper (AA 141-240) (AbBy Fluor® 680)

ALOXE3 Reaktivität: Human IF (p), IF (cc) Wirt: Kaninchen Polyclonal AbBy Fluor® 680
Produktnummer ABIN4996332
  • Target Alle ALOXE3 Antikörper anzeigen
    ALOXE3 (Arachidonate Lipoxygenase 3 (ALOXE3))
    Bindungsspezifität
    • 14
    • 8
    • 7
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 141-240
    Reaktivität
    • 39
    • 8
    Human
    Wirt
    • 37
    • 2
    Kaninchen
    Klonalität
    • 38
    Polyklonal
    Konjugat
    • 16
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ALOXE3 Antikörper ist konjugiert mit AbBy Fluor® 680
    Applikation
    • 24
    • 18
    • 12
    • 12
    • 5
    • 4
    • 3
    • 1
    • 1
    Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Pig,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human ALOXE3
    Isotyp
    IgG
    Top Product
    Discover our top product ALOXE3 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    ALOXE3 (Arachidonate Lipoxygenase 3 (ALOXE3))
    Andere Bezeichnung
    ALOXE3 (ALOXE3 Produkte)
    Synonyme
    e-lox antikoerper, elox3 antikoerper, ARCI3 antikoerper, E-LOX antikoerper, eLOX3 antikoerper, e-LOX-3 antikoerper, ALOX15B antikoerper, arachidonate lipoxygenase 3 antikoerper, arachidonate lipoxygenase 3 L homeolog antikoerper, arachidonate 15-lipoxygenase, type B antikoerper, ALOXE3 antikoerper, aloxe3.L antikoerper, aloxe3 antikoerper, Aloxe3 antikoerper, ALOX15B antikoerper
    Hintergrund

    Synonyms: ALOXE3, Arachidonate lipoxygenase 3, e LOX 3, E LOX, e-LOX-3, eLOX3, Epidermal lipoxygenase, Epidermis-type lipoxygenase 3, Lipoxygenase 3, LOXE3_HUMAN.

    Background: Introduces molecular oxygen into polyunsaturated fatty acids. Exact substrate is not known.Tissue specificity:Predominantly expressed in skin.Involvement in diseaseDefects in ALOXE3 are a cause of non-bullous congenital ichthyosiform erythroderma (NCIE). NCIE is a non-bullous ichthyosis, a skin disorder characterized by abnormal cornification of the epidermis. Most affected individuals are born with a tight, shiny, translucent covering called collodion membrane. The collodion membrane subsequently evolves into generalized scaling and intense redness of the skin. Clinical features are milder than in lamellar ichthyoses and demonstrate a greater variability in the intensity of erythema, size and type of scales. In contrast to lamellar ichthyoses, scales are usually white, fine and powdery, and palms and soles are severely affected. Patients suffer from palmoplantar keratoderma, often with painful fissures, digital contractures, and loss of pulp volume.

    Gen-ID
    59344
    Pathways
    Cell-Cell Junction Organization
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