ANKRD20A3 Antikörper (AbBy Fluor® 750)
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- Target Alle ANKRD20A3 Produkte
- ANKRD20A3 (Ankyrin Repeat Domain 20 Family, Member A3 (ANKRD20A3))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ANKRD20A3 Antikörper ist konjugiert mit AbBy Fluor® 750
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Applikation
- Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human ANKRD20A3
- Isotyp
- IgG
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- Applikationshinweise
- IF(IHC-P) 1:50-200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- ANKRD20A3 (Ankyrin Repeat Domain 20 Family, Member A3 (ANKRD20A3))
- Andere Bezeichnung
- ANKRD20A3 (ANKRD20A3 Produkte)
- Synonyme
- ankyrin repeat domain 20 family member A3 antikoerper, ANKRD20A3 antikoerper
- Hintergrund
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Synonyms: Ankyrin repeat domain 20 family member A3, Ankyrin repeat domain 20A related, Ankyrin repeat domain containing protein 20A3, MGC176486, MGC198508, A20A3_HUMAN.
Background: Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD20A (ankyrin repeat domain-containing protein 20A) is an 823 amino acid protein that contains five ANK repeats. The gene encoding ANKRD20A maps to chromosome 9, which consists of about 145 million bases and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and familial dysautonomia are associated with chromosome 9. Also, chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.
- Gen-ID
- 441425
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