NAE1 Antikörper (AA 401-500) (AbBy Fluor® 750)
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- Target Alle NAE1 Antikörper anzeigen
- NAE1 (NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))
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Bindungsspezifität
- AA 401-500
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Reaktivität
- Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser NAE1 Antikörper ist konjugiert mit AbBy Fluor® 750
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Maus, Ratte
- Homologie
- Human,Dog,Pig,Horse,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human APPBP1
- Isotyp
- IgG
- Top Product
- Discover our top product NAE1 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- NAE1 (NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))
- Andere Bezeichnung
- APPBP1 (NAE1 Produkte)
- Synonyme
- APPBP1 antikoerper, CG7828 antikoerper, Dmel\\CG7828 antikoerper, anon-WO0140519.225 antikoerper, dAPP-BP1 antikoerper, dAPPBP1 antikoerper, A-116A10.1 antikoerper, ula-1 antikoerper, Appbp1 antikoerper, 59kDa antikoerper, appbp1 antikoerper, zgc:66148 antikoerper, beta-Amyloid precursor protein binding protein 1 antikoerper, NEDD8 activating enzyme E1 subunit 1 antikoerper, NEDD8 activating enzyme E1 subunit 1 S homeolog antikoerper, nedd8 activating enzyme E1 subunit 1 antikoerper, NEDD8-activating enzyme E1 regulatory subunit antikoerper, APP-BP1 antikoerper, NAE1 antikoerper, Nae1 antikoerper, nae1.S antikoerper, nae1 antikoerper, ula-1 antikoerper
- Hintergrund
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Synonyms: HPP1, ula-1, APPBP1, A-116A10.1, NEDD8-activating enzyme E1 regulatory subunit, Amyloid beta precursor protein-binding protein 1, 59 kDa, APP-BP1, Amyloid protein-binding protein 1, Proto-oncogene protein 1, NAE1
Background: Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Necessary for cell cycle progression through the S-M checkpoint. Overexpression of NAE1 causes apoptosis through deregulation of NEDD8 conjugation.
- Gen-ID
- 8883
- UniProt
- Q13564
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