ARFIP2 Antikörper (AA 221-341) (AbBy Fluor® 680)
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- Target Alle ARFIP2 Antikörper anzeigen
- ARFIP2 (ADP-Ribosylation Factor Interacting Protein 2 (ARFIP2))
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Bindungsspezifität
- AA 221-341
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ARFIP2 Antikörper ist konjugiert mit AbBy Fluor® 680
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Arfaptin 2
- Isotyp
- IgG
- Top Product
- Discover our top product ARFIP2 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- ARFIP2 (ADP-Ribosylation Factor Interacting Protein 2 (ARFIP2))
- Andere Bezeichnung
- Arfaptin 2 (ARFIP2 Produkte)
- Synonyme
- POR1 antikoerper, 2310002N04Rik antikoerper, POR antikoerper, Por1 antikoerper, ARFIP2 antikoerper, im:7136059 antikoerper, zgc:112066 antikoerper, ADP ribosylation factor interacting protein 2 antikoerper, ADP-ribosylation factor interacting protein 2 antikoerper, ADP-ribosylation factor interacting protein 2b antikoerper, ARFIP2 antikoerper, Arfip2 antikoerper, arfip2b antikoerper
- Hintergrund
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Synonyms: ARFIP2, arfaptin 2, ADP-ribosylation factor interacting protein 2, Partner of RAC1, POR1, ARFP2_HUMAN .
Background: ARFIP2 is a ubiquitously expressed protein implicated in mediating cross talk between RAC and ARF small GTPases. It has been shown that ARFIP2 binds specifically to GTP-bound ARF1 and ARF6, but binds to Rac-GTP and Rac-GDP with similar affinities. The X-ray structure of arfaptin reveals an elongated, crescent-shaped dimer of 3-helix coiled-coils. Structures of arfaptin with Rac bound to either GDP or the slowly hydrolysable analog GMPPNP show that the switch regions adopt similar conformations in both complexes.
- Gen-ID
- 23647
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