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CUEDC2 Antikörper (C-Term)

CUEDC2 Reaktivität: Human, Maus, Ratte WB, IF, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN499688
  • Target Alle CUEDC2 Antikörper anzeigen
    CUEDC2 (CUE Domain Containing 2 (CUEDC2))
    Bindungsspezifität
    • 15
    • 8
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 35
    • 24
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 48
    • 2
    Kaninchen
    Klonalität
    • 48
    • 2
    Polyklonal
    Konjugat
    • 26
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CUEDC2 Antikörper ist unkonjugiert
    Applikation
    • 37
    • 14
    • 13
    • 13
    • 10
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody reacts to CUEDC2.
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    CUEDC2 antibody was raised against a 19 amino acid peptide from near the carboxy terminus of human CUEDC2.
    Isotyp
    IgG
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  • Applikationshinweise
    ELISA. Western Blot: CUEDC2 antibody can be used for detection of CUEDC2 at 1 - 2 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C.
  • Target
    CUEDC2 (CUE Domain Containing 2 (CUEDC2))
    Andere Bezeichnung
    CUEDC2 (CUEDC2 Produkte)
    Synonyme
    cuedc2 antikoerper, MGC81368 antikoerper, C10orf66 antikoerper, bA18I14.5 antikoerper, 3010002G01Rik antikoerper, wu:fi42e02 antikoerper, zgc:92255 antikoerper, CUE domain containing 2 S homeolog antikoerper, CUE domain containing 2 antikoerper, CUE domain containing 2 L homeolog antikoerper, cuedc2.S antikoerper, CUEDC2 antikoerper, cuedc2.L antikoerper, cuedc2 antikoerper, Cuedc2 antikoerper
    Hintergrund
    The CUE (coupling of ubiquitin conjugation to endoplasmic reticulum degradation) domain is an evolutionarily conserved, ~40 amino acid monoubiquitin-binding domain that mediates intramolecular monoubiquitylation. CUE domains are present in eukaryotic proteins that are involved in ubiquitination and protein trafficking pathways and may be required for ubiquitination of the proteins in which they are found. CUEDC2 (CUE domain-containing protein 2) was found through a yeast two-hybrid screening as a protein that interacts with the progesterone receptor (PR) and promotes progesterone-induced PR degradation by the ubiquitin-proteasome pathway. CUEDC2 also decreases the sumoylation of PR. CUEDC2 has also been found to interact with IKK-a and IKK-b and decrease the activation of NF-kB by decreasing the activation of IKK. CUEDC2 antibody will not cross-react with CUEDC1.Synonyms: C10orf66, CUE domain-containing protein 2, HOYS6
    Gen-ID
    79004
    NCBI Accession
    NP_076945
    UniProt
    Q9H467
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