CX3CR1 Antikörper (N-Term)

Produktnummer ABIN499692

Produktdetails anti-CX3CR1 Antikörper

Target: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CX3CR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: CX3CR1 antibody was raised against a peptide corresponding to amino acids 2 to 21 of human CX3CR1. The sequence differs from those of mouse and rat CX3CR1 by four amino acids (3,4).

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Human CX3CR1 (N-Terminus) Peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: CX3CR1 antibody can be used for detection of CX3CR1 at 1/500 to 1/2000dilution. An approximately 50 kDa band can be detected. Immunohistochemistry. FACS.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Referenzen für anti-CX3CR1 Antikörper (ABIN499692)

Wei, Cao, Yu, Liu, Wang: "Overexpression of CX3CR1 is associated with cellular metastasis, proliferation and survival in gastric cancer." in: Oncology reports, Vol. 33, Issue 2, pp. 615-24, (2015) (PubMed).

Details zu CX3CR1

Target: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Andere Bezeichnung: CX3CR1 / GPR13 (CX3CR1 Produkte)

Synonyme: CCRL1 antikoerper, CMKBRL1 antikoerper, CMKDR1 antikoerper, GPR13 antikoerper, GPRV28 antikoerper, V28 antikoerper, Rbs11 antikoerper, C-X3-C motif chemokine receptor 1 antikoerper, chemokine (C-X3-C motif) receptor 1 antikoerper, CX3C chemokine receptor 1 antikoerper, CX3CR1 antikoerper, Cx3cr1 antikoerper, LOC100559882 antikoerper

Hintergrund: CX3CR1 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human, murine, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively, (1-4). The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1 (5). Recently, CX3CR1 was found to serve as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine (6). CX3CR1 mediates leukocyte migration and adhesion (5). CX3CR1 is expressed in a variety of human tissues and cell lines (2).Synonyms: Beta chemokine receptor-like 1, C-X3-C CKR-1, CMK-BRL-1, CMKBRL1, CX3C chemokine receptor 1, Fractalkine receptor, G-protein coupled receptor 13, V28

Gen-ID: 1524

NCBI Accession: NP_001328

UniProt: P49238

Pathways: Cellular Response to Molecule of Bacterial Origin