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FAM120A Antikörper (Center)

FAM120A Reaktivität: Human, Maus, Ratte WB, IF, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN499822
  • Target Alle FAM120A Antikörper anzeigen
    FAM120A (Family with Sequence Similarity 120A (FAM120A))
    Bindungsspezifität
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reaktivität
    • 9
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 8
    • 1
    Kaninchen
    Klonalität
    • 8
    • 1
    Polyklonal
    Konjugat
    • 9
    Dieser FAM120A Antikörper ist unkonjugiert
    Applikation
    • 9
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody reacts to FAM120A.
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    FAM120A antibody was raised against an 18 amino acid peptide from near the center of human FAM120A.
    Isotyp
    IgG
    Top Product
    Discover our top product FAM120A Primärantikörper
  • Applikationshinweise
    ELISA. Western Blot: 0.5 - 1 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C.
  • Target
    FAM120A (Family with Sequence Similarity 120A (FAM120A))
    Andere Bezeichnung
    FAM120A (FAM120A Produkte)
    Synonyme
    MGC89333 antikoerper, fam120a antikoerper, C9orf10 antikoerper, Ossa antikoerper, DNAPTP1 antikoerper, DNAPTP5 antikoerper, OSSA antikoerper, RGD1306643 antikoerper, family with sequence similarity 120A antikoerper, family with sequence similarity 120, member A antikoerper, fam120a antikoerper, Fam120a antikoerper, FAM120A antikoerper
    Hintergrund
    FAM120A (C9orf10) is a member of the constitutive coactivator of PPAR gamma family and the gene was mapped to chromosome 9q22.31. FAM120A was recently detected within the Pur-alpha-containing mRNA-protein complex in the brain. As a novel RNA-binding protein, FAM120A is a critical component of the oxidative stress-induced survival signaling. It may participate in mRNA transport in the cytoplasm. FAM120A activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. FAM120A protects cells from apoptosis through activation of SRKs in response to oxidative stress. Blocking of the survival signaling mediated by FAM120A, which sensitizes the cancer cells to stress-induced apoptosis, may be a novel therapeutic approach for gastric scirrhous carcinoma cells.Synonyms: C9orf10, Constitutive coactivator of PPAR-gamma-like protein 1, KIAA0183, OSSA, Oxidative stress-associated Src activator, Protein FAM120A
    Gen-ID
    23196
    NCBI Accession
    NP_055427
    UniProt
    Q9NZB2
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