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FAM59A Antikörper (C-Term)

FAM59A Reaktivität: Human, Maus, Ratte WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN499824
  • Target Alle FAM59A Antikörper anzeigen
    FAM59A (Family with Sequence Similarity 59, Member A (FAM59A))
    Bindungsspezifität
    • 15
    • 5
    • 1
    • 1
    C-Term
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 21
    Kaninchen
    Klonalität
    • 21
    Polyklonal
    Konjugat
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FAM59A Antikörper ist unkonjugiert
    Applikation
    • 16
    • 13
    • 13
    • 8
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    FAM59A antibody was raised against a 19 amino acid peptide from near the carboxy terminus of human FAM59A.
    Isotyp
    IgG
    Top Product
    Discover our top product FAM59A Primärantikörper
  • Applikationshinweise
    ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store the antibody (in aliquots) at -20 °C.
  • Target
    FAM59A (Family with Sequence Similarity 59, Member A (FAM59A))
    Andere Bezeichnung
    FAM59A (FAM59A Produkte)
    Synonyme
    C18orf11 antikoerper, FAM59A antikoerper, Gm944 antikoerper, C86169 antikoerper, Fam59a antikoerper, mKIAA4238 antikoerper, fam59a antikoerper, zgc:55634 antikoerper, GRB2 associated regulator of MAPK1 subtype 1 antikoerper, GRB2 associated, regulator of MAPK1 antikoerper, GAREM1 antikoerper, Garem1 antikoerper, garem antikoerper
    Hintergrund
    FAM59A, also known as GAREM, was initially identified through a mass spectroscoptic method that measures different phosphotyrosine states of proteins in response to different cell stimuli. FAM59A is a downstream molecule in the EGF signaling pathway that is tyrosine-phosphorylated, and this phosphorylation is needed for the binding of Grb2, an adaptor protein crucial to the transduction of growth signals from the plasma membrane to the nucleus. ERK activation in response to EGF stimulation is regulated by FAM59A in COS-7 and HeLa cells, and the overexpression of FAM59A stimulated cell proliferation and colony formation in soft agar, suggesting that FAM59A might be a critical protein with roles in ligand-mediated signaling pathway of the EGF receptor and the tumorigenesis of cells.Synonyms: C18orf11
    Gen-ID
    64762
    UniProt
    Q9H706
    Pathways
    EGFR Signaling Pathway
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