FEZ2
Reaktivität: Ratte, Maus
WB, IF (cc), IF (p)
Wirt: Kaninchen
Polyclonal
AbBy Fluor® 750
Applikationshinweise
ELISA. Western Blot: 0.5 - 1 μg/mL. Immunofluorescence. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C.
Target
FEZ2
(Fasciculation and Elongation Protein zeta 2 (Zygin II) (FEZ2))
HUM3CL antikoerper, 9030616F16 antikoerper, D17Ertd315e antikoerper, Zrp antikoerper, fasciculation and elongation protein zeta 2 antikoerper, fasciculation and elongation protein zeta 2 (zygin II) antikoerper, FEZ2 antikoerper, Fez2 antikoerper
Hintergrund
Fasciculation and elongation protein zeta-2 (FEZ2) is a homolog to the mammalian FEZ1, itself an ortholog of the C. elegans UNC-76. In contrast to FEZ1, FEZ2 mRNA is widely expressed in mouse tissues. FEZ2 interacts with protein kinase C (PKC)-z substrate and induces neurite extension of PC12 cells when co-expressed with a constitutively active form of PKC-z, suggesting FEZ2 may play an important role in the morphological changes of various cells by associating with PKC-z in a tissue non-specific manner. FEZ2 can interact with FEZ1 through its c-terminal regions and especially its coiled-coil region. At least two isoforms of FEZ2 are known to exist.Synonyms: FEZ2, Fasciculation and elongation protein zeta-2, Zygin II