FBLN3 Antikörper (C-Term)
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- Target Alle FBLN3 Antikörper anzeigen
- FBLN3 (Fibulin 3 (FBLN3))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser FBLN3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody reacts to Fibulin 3.
- Aufreinigung
- Affinity chromatography purified via peptide column
- Immunogen
- Fibulin 3 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human Fibulin 3.
- Isotyp
- IgG
- Top Product
- Discover our top product FBLN3 Primärantikörper
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- Applikationshinweise
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ELISA. Western Blot: 0.5 - 1 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS containing 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C.
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- Target
- FBLN3 (Fibulin 3 (FBLN3))
- Andere Bezeichnung
- Fibulin-3 (FBLN3 Produkte)
- Synonyme
- DHRD antikoerper, DRAD antikoerper, FBLN3 antikoerper, FBNL antikoerper, FIBL-3 antikoerper, MLVT antikoerper, MTLV antikoerper, S1-5 antikoerper, T16 antikoerper, EGF containing fibulin like extracellular matrix protein 1 antikoerper, EGF-containing fibulin-like extracellular matrix protein 1 antikoerper, epidermal growth factor-containing fibulin-like extracellular matrix protein 1 antikoerper, EFEMP1 antikoerper, Efemp1 antikoerper
- Hintergrund
- Fibulin 3, also known as epidermal growth factor (EGF)-containing fibulin-like extracellular matrix protein 1 (EFEMP1), is a member of the fibulin family of extracellular glycoproteins, a group of proteins that are widely distributed and frequently associated with vascular and elastic tissues. The fibulin proteins typically contain a tandem array of EGF-like repeats and a fibulin-type COOH-terminal module. Aberrant accumulation of Fibulin 3 in the endoplasmic reticulum of retinal pigment epithelial cells has been shown to be associated with inherited forms of macular degeneration, but the loss of Fibulin 3 expression does not lead to macular degeneration but rather the appearance of hernias due to a reduction of elastic fibers of fascial connective tissue. Recent experiments have shown that expression of Fibulin 3 promotes tumor growth and may thus be a therapeutic target. At least three isoforms of Fibulin 3 are known to exist. This antibody is predicted to not cross-react with other Fibulin proteins.Synonyms: DHRD, DRAD, EFEMP1, EGF-containing fibulin-like extracellular matrix protein 1, Extracellular protein S1-5, FBLN3, FBNL, Fibrillin-like protein, Fibulin 3, MLVT, MTLV, S1-5
- Gen-ID
- 2202
- NCBI Accession
- NP_004096
- UniProt
- Q12805
- Pathways
- EGFR Signaling Pathway
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