Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

FLASH Antikörper (C-Term)

CASP8AP2 Reaktivität: Human WB, IF, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN499842
  • Target Alle FLASH (CASP8AP2) Antikörper anzeigen
    FLASH (CASP8AP2) (CASP8 Associated Protein 2 (CASP8AP2))
    Bindungsspezifität
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 17
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 20
    Kaninchen
    Klonalität
    • 20
    Polyklonal
    Konjugat
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FLASH Antikörper ist unkonjugiert
    Applikation
    • 13
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Spezifität
    FLASH antibody was raised against a synthetic peptide corresponding to amino acids near the carboxy-terminus of human FLASH which differ from those of mouse by one amino acid.
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    Human FLASH (C-Terminus) Peptide
    Isotyp
    IgG
    Top Product
    Discover our top product CASP8AP2 Primärantikörper
  • Applikationshinweise
    ELISA. Western Blot: 0.25 to 0.5 μg/mL. An approximate 220 kDa band can be detected. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C.
  • Target
    FLASH (CASP8AP2) (CASP8 Associated Protein 2 (CASP8AP2))
    Andere Bezeichnung
    CASP8AP2 / FLASH (CASP8AP2 Produkte)
    Synonyme
    CASP8AP2 antikoerper, FLASH antikoerper, fc74h10 antikoerper, wu:fc74h10 antikoerper, zgc:113449 antikoerper, CED-4 antikoerper, RIP25 antikoerper, AA387232 antikoerper, D4Ertd659e antikoerper, mKIAA1315 antikoerper, caspase 8 associated protein 2 antikoerper, CASP8AP2 antikoerper, casp8ap2 antikoerper, Casp8ap2 antikoerper
    Hintergrund
    A novel mammalian CED-4 homologous was recently identified and cloned in mouse (1) and human (2) and designated FLASH (for FLICE-associated huge protein). FLASH is involved in Fas induced apoptosis. It is recruited to Fas after the receptor cross-linking. Overexpression of wild type of FLASH facilitates and its dominant negative form inhibits Fas induced apoptosis. FLASH interacts with the DEDs of caspase-8 and FADD through the DED-like domain of FLASH and mediates activation of caspase-8 (1). There are parallels between FLASH and Apaf-1/CED-4 although there are arguments against their structural similarity (1,2). FLASH is widely expressed.Synonyms: CASP8-associated protein 2, KIAA1315, RIP25
    Gen-ID
    9994
    UniProt
    Q9Y563
    Pathways
    Chromatin Binding, Positive Regulation of Endopeptidase Activity
Sie sind hier:
Kundenservice