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FNIP2 Antikörper (C-Term)

FNIP2 Reaktivität: Human, Maus, Ratte WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN499853
  • Target Alle FNIP2 Antikörper anzeigen
    FNIP2 (Folliculin Interacting Protein 2 (FNIP2))
    Bindungsspezifität
    • 9
    • 8
    • 7
    • 3
    • 1
    • 1
    C-Term
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 19
    Kaninchen
    Klonalität
    • 19
    Polyklonal
    Konjugat
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser FNIP2 Antikörper ist unkonjugiert
    Applikation
    • 19
    • 15
    • 14
    • 14
    • 5
    • 2
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody reacts to FNIP2.
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    FNIP2 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human FNIP2.
    Isotyp
    IgG
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  • Applikationshinweise
    ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C.
  • Target
    FNIP2 (Folliculin Interacting Protein 2 (FNIP2))
    Andere Bezeichnung
    FNIP2 (FNIP2 Produkte)
    Synonyme
    LOC797213 antikoerper, FNIPL antikoerper, MAPO1 antikoerper, D630023B12Rik antikoerper, mKIAA1450 antikoerper, RGD1562174 antikoerper, folliculin interacting protein 2 antikoerper, si:ch211-42i9.8 antikoerper, FNIP2 antikoerper, si:ch211-42i9.8 antikoerper, fnip2 antikoerper, Fnip2 antikoerper
    Hintergrund
    FNIP2 is the second protein found to interact with folliculin, the product of the Birt-Hogg-Dube (BHD) gene. Folliculin is thought to act as a tumor suppressor as mutations or loss of heterozygosity in this gene are associated with BHD syndrome-related renal tumors. Folliculin and FNIP1, a protein that shares 49 % identity to FNIP2, bind to AMPK, an important energy sensor in cells that negatively regulates the mammalian target of rapamycin (mTOR), a protein that is thought to be the master switch for cell growth and proliferation. FNIP1 and FNIP2 are able to form homo- and heteromeric multimers, suggesting these proteins may have a functional relationship. Multiple isoforms of FNIP2 are known to exist. This antibody is predicted to not cross-react with FNIP1.Synonyms: FNIP1-like protein, FNIPL, Folliculin-interacting protein 2, KIAA1450, MAPO1, O6-methylguanine-induced apoptosis 1 protein
    Gen-ID
    57600
    NCBI Accession
    NP_065891
    UniProt
    Q9P278
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