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FNIP2 Antikörper (N-Term)

FNIP2 Reaktivität: Human, Maus, Ratte WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN499855
  • Target Alle FNIP2 Antikörper anzeigen
    FNIP2 (Folliculin Interacting Protein 2 (FNIP2))
    Bindungsspezifität
    • 10
    • 8
    • 7
    • 2
    • 1
    • 1
    N-Term
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 19
    Kaninchen
    Klonalität
    • 19
    Polyklonal
    Konjugat
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser FNIP2 Antikörper ist unkonjugiert
    Applikation
    • 19
    • 15
    • 14
    • 14
    • 5
    • 2
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody reacts to FNIP2.
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    FNIP2 antibody was raised against an 18 amino acid peptide near the amino terminus of human FNIP2.
    Isotyp
    IgG
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  • Applikationshinweise
    ELISA. Wsetern Blot: 1 - 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C.
  • Target
    FNIP2 (Folliculin Interacting Protein 2 (FNIP2))
    Andere Bezeichnung
    FNIP2 (FNIP2 Produkte)
    Synonyme
    LOC797213 antikoerper, FNIPL antikoerper, MAPO1 antikoerper, D630023B12Rik antikoerper, mKIAA1450 antikoerper, RGD1562174 antikoerper, folliculin interacting protein 2 antikoerper, si:ch211-42i9.8 antikoerper, FNIP2 antikoerper, si:ch211-42i9.8 antikoerper, fnip2 antikoerper, Fnip2 antikoerper
    Hintergrund
    FNIP2 is the second protein found to interact with folliculin, the product of the Birt-Hogg-Dube (BHD) gene. Folliculin is thought to act as a tumor suppressor as mutations or loss of heterozygosity in this gene are associated with BHD syndrome-related renal tumors. Folliculin and FNIP1, a protein that shares 49 % identity to FNIP2, bind to AMPK, an important energy sensor in cells that negatively regulates the mammalian target of rapamycin (mTOR), a protein that is thought to be the master switch for cell growth and proliferation. FNIP1 and FNIP2 are able to form homo- and heteromeric multimers, suggesting these proteins may have a functional relationship. Multiple isoforms of FNIP2 are known to exist. This antibody is predicted to not cross-react with FNIP1.Synonyms: FNIP1-like protein, FNIPL, Folliculin-interacting protein 2, KIAA1450, MAPO1, O6-methylguanine-induced apoptosis 1 protein
    Gen-ID
    57600
    NCBI Accession
    NP_065891
    UniProt
    Q9P278
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