Gastrin Antikörper (C-Term)
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- Target Alle Gastrin (GAST) Antikörper anzeigen
- Gastrin (GAST)
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Gastrin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Aufreinigung
- Affinity chromatography purified via peptide column
- Immunogen
- GAS antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human GAS.
- Isotyp
- IgG
- Top Product
- Discover our top product GAST Primärantikörper
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- Applikationshinweise
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ELISA. Western Blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- PBS containing 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store the antibody (in aliquots) at -20 °C.
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- Target
- Gastrin (GAST)
- Andere Bezeichnung
- GAS (GAST Produkte)
- Synonyme
- GAS antikoerper, Gas antikoerper, PPG34 antikoerper, GAST antikoerper, gastrin antikoerper, GAST antikoerper, Gast antikoerper
- Hintergrund
- Steroid receptor co-activators (SRCs) were initially described as nuclear receptor transcription co-activators, but they have recently been determined to co-regulate transcription initiated by other transcription factors. GAS is a recently identified glutamate-rich protein that interacts with SRC1, but not GRIP1 or AIB1, the other two members of the SRC family. GAS can also interact with the alpha subunit of the estrogen receptor (ERa), but not other receptors such as the retinoic acid receptor a, suggesting the interaction between GAS and ERa is relatively specific. Depletion of GAS by RNA interference in MCF7 cells led to a decrease in the mRNA and protein levels of ER target genes such as pS2, c-Myc and cyclin D1, indicating the role of GAS in the regulation of ER target genes. GAS has also been found to associate with an SET1-like methyltransferase complex specific for H3K4 methylation, suggesting that GAS has multiple roles in transcriptional regulation.Synonyms: Glutamate-rich coactivator interacting with SRC1, PA1, PTIP-associated 1 protein
- Gen-ID
- 2716513
- NCBI Accession
- NP_078792
- UniProt
- P08315
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