CARD14 Antikörper (AA 1-100) (AbBy Fluor® 750)
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- Target Alle CARD14 Antikörper anzeigen
- CARD14 (Caspase Recruitment Domain Family, Member 14 (CARD14))
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Bindungsspezifität
- AA 1-100
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CARD14 Antikörper ist konjugiert mit AbBy Fluor® 750
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human, Maus
- Homologie
- Rat,Dog,Cow,Sheep,Pig,Horse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human CARD14
- Isotyp
- IgG
- Top Product
- Discover our top product CARD14 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- CARD14 (Caspase Recruitment Domain Family, Member 14 (CARD14))
- Andere Bezeichnung
- CARD14 (CARD14 Produkte)
- Synonyme
- BIMP2 antikoerper, CARMA2 antikoerper, PRP antikoerper, PSORS2 antikoerper, PSS1 antikoerper, Bimp2 antikoerper, caspase recruitment domain family member 14 antikoerper, caspase recruitment domain family, member 14 antikoerper, CARD14 antikoerper, Card14 antikoerper
- Hintergrund
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Synonyms: Bcl10 interacting MAGUK protein 2, Bimp 2, Bimp2, CARD 14, CARD containing MAGUK 2 protein, CARD containing MAGUK protein 2, Card maguk protein 2, Carma 2, Carma2, Caspase recruitment domain containing protein 14, Caspase recruitment domain family member 14, Caspase recruitment domain protein 14, CAR14_HUMAN.
Background: The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein shares a similar domain structure with CARD11 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. Two alternatively spliced variants of this gene encoding distinct isoforms have been reported.
- Gen-ID
- 79092
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