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IER3 Antikörper (Center)

IER3 Reaktivität: Human, Maus WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN499960
  • Target Alle IER3 Antikörper anzeigen
    IER3 (Immediate Early Response 3 (IER3))
    Bindungsspezifität
    • 15
    • 8
    • 7
    • 6
    • 5
    • 2
    • 1
    Center
    Reaktivität
    • 32
    • 19
    • 14
    • 4
    • 4
    • 4
    Human, Maus
    Wirt
    • 47
    Kaninchen
    Klonalität
    • 47
    Polyklonal
    Konjugat
    • 10
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IER3 Antikörper ist unkonjugiert
    Applikation
    • 36
    • 20
    • 14
    • 14
    • 13
    • 13
    • 13
    • 6
    • 5
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody reacts to IEX1.
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    IEX1 antibody was raised against a 24 amino acid peptide near the center of human IEX1.
    Isotyp
    IgG
    Top Product
    Discover our top product IER3 Primärantikörper
  • Applikationshinweise
    ELISA. Western Blot: 2 - 4 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C.
  • Target
    IER3 (Immediate Early Response 3 (IER3))
    Andere Bezeichnung
    IER3 / IEX1 (IER3 Produkte)
    Synonyme
    DIF-2 antikoerper, DIF2 antikoerper, GLY96 antikoerper, IEX-1 antikoerper, IEX-1L antikoerper, IEX1 antikoerper, PRG1 antikoerper, AI663993 antikoerper, cI-3 antikoerper, gly96 antikoerper, IER3 antikoerper, Dif2 antikoerper, Iex1 antikoerper, Ler3 antikoerper, Prg1 antikoerper, immediate early response 3 antikoerper, IER3 antikoerper, Ier3 antikoerper
    Hintergrund
    IEX-1 is a stress inducible gene that is induced by ionizing radiation, ultraviolet radiation, and a variety of growth factors, i.e., FAS and TNF-a. IEX-1 is widely expressed in epithelial and endocrine tissues, as well as in vascular endothelium. It plays an important role in the regulation of cellular growth, cell death and oncogenesis. IEX-1 is precisely regulated by multiple transcription factors such as p53, NF-kappaB/rel, Sp1 and c-Myc, to ensure rapid and transient expression of IEX-1 in cells under a variety of stress conditions. IEX-1 is expressed as both a longer form (IEX1L) and a splice variant, designated IEX1S. It is localized to the nucleus and perinuclear region. Overexpression of IEX-1 facilitates apoptosis and cell cycle progression, whereas disruption of IEX-1 expression is associated with decreases in both apoptosis and cell cycle progression.Synonyms: DIF2, Differentiation-dependent gene 2 protein, GLY96, IEX-1, Immediate early protein GLY96, Immediate early response 3 protein, PACAP-responsive gene 1 protein, PRG1, Radiation-inducible immediate-early gene IEX-1
    Gen-ID
    8870
    UniProt
    P46695
    Pathways
    Regulation of Carbohydrate Metabolic Process
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