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FBXO43 Antikörper (C-Term)

FBXO43 Reaktivität: Human WB, IF, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN499984
  • Target Alle FBXO43 Antikörper anzeigen
    FBXO43 (F-Box Protein 43 (FBXO43))
    Bindungsspezifität
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 10
    • 3
    • 2
    • 1
    Human
    Wirt
    • 9
    • 2
    • 1
    Kaninchen
    Klonalität
    • 10
    • 2
    Polyklonal
    Konjugat
    • 12
    Dieser FBXO43 Antikörper ist unkonjugiert
    Applikation
    • 11
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Spezifität
    IL-1RAcP antibody was raised against a peptide corresponding to amino acids near the carboxy terminus of IL-1RAcP, which differs from the sequence of mouse origin by three amino acids. It has no cross activity to other member in the IL-1 receptor family.
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    Human IL-1RAcP (C-Terminus) Peptide
    Isotyp
    IgG
    Top Product
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  • Applikationshinweise
    ELISA. Western Blot: 1/500 to 1/1000. An approximately 66 kDa band can be detected.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
  • Target
    FBXO43 (F-Box Protein 43 (FBXO43))
    Andere Bezeichnung
    FBXO43 (FBXO43 Produkte)
    Synonyme
    EMI2 antikoerper, ERP1 antikoerper, FBX43 antikoerper, 4930533G20Rik antikoerper, Emi2 antikoerper, emi2 antikoerper, erp1 antikoerper, Xerp1 antikoerper, zgc:66488 antikoerper, F-box protein 43 antikoerper, F-box protein 43 L homeolog antikoerper, FBXO43 antikoerper, Fbxo43 antikoerper, fbxo43 antikoerper, fbxo43.L antikoerper
    Hintergrund
    The pro-inflammatory cytokine IL-1 induced cellular response requires two subunits of its receptor, IL-1 receptor I(IL-1RI) and IL-1 receptor accessory protein (IL-1RAcP) (1).IL-1 RAcP forms a complex with IL-1RI in response to IL-1 treatment. The IL-1 receptor-associated kinase (IRAK), which mediates activation of NF-kappaB inducing kinae (NIK) and of NF-kappaB, recruites to the IL-1R complex through IL-1 RAcP(2). IL-1 activation of stress-activated protein kinase and of acid sphingomyelinase also requires IL-1RAcP(3,4). Like IL-1RI, IL-1RAcP subunit is essential for IL-1 mediated cellular response. IL-1RAcP is expressed in many tissues.Synonyms: EMI2, Endogenous meiotic inhibitor 2, F-box only protein 43, FBP5B
    Gen-ID
    100101275
    UniProt
    Q8AXF4
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