IL21 Receptor Antikörper (Extracellular Domain)

Produktnummer ABIN499988

Produktdetails anti-IL21 Receptor Antikörper

Target: IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))

Bindungsspezifität: Extracellular Domain

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL21 Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: IL-21 receptor antibody was raised against a synthetic peptide corresponding to amino acids 97 to 111 of human IL-21 receptor precursor.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Human IL-21 Receptor (Extracellular Domain) Peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: 0.5 to 1 μg/mL. An approximately 60 kDa band can be detected. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Details zu IL21 Receptor

Target: IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))

Andere Bezeichnung: Interleukin-21 Receptor / IL21R (IL21R Produkte)

Synonyme: IL21R antikoerper, il-21ra.a antikoerper, CD360 antikoerper, NILR antikoerper, interleukin 21 receptor antikoerper, interleukin 21 receptor, tandem duplicate 1 antikoerper, IL21R antikoerper, il21r.1 antikoerper, Il21r antikoerper

Hintergrund: A novel cytokine related to IL-2 and IL-15 was recently identified and designated IL-21 . The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family (1,2). IL-21R forms a complex with the common cytokine receptor g chain, gc, and mediates IL-21 signaling (3,4). Both IL-21R and the gc are necessary for the IL-21 function. IL-21 and its receptor activate JAK-STAT signaling pathway. IL-21R is expressed in spleen, thymus, natural killer (NK), T and B cell lines. IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations.Synonyms: IL-21R, IL21 receptor, NILR, Novel interleukin receptor

Gen-ID: 50615

NCBI Accession: NP_068570

UniProt: Q9HBE5

Pathways: JAK-STAT Signalweg