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IL23A Antikörper (C-Term)

IL23A Reaktivität: Human, Maus WB, IF, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN499996
  • Target Alle IL23A Antikörper anzeigen
    IL23A (Interleukin 23, alpha subunit p19 (IL23A))
    Bindungsspezifität
    • 8
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 42
    • 17
    • 8
    • 1
    Human, Maus
    Wirt
    • 34
    • 8
    • 2
    • 1
    Kaninchen
    Klonalität
    • 37
    • 8
    Polyklonal
    Konjugat
    • 31
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IL23A Antikörper ist unkonjugiert
    Applikation
    • 30
    • 20
    • 7
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody reacts to IL-23.
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    IL-23 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human IL-23.
    Isotyp
    IgG
    Top Product
    Discover our top product IL23A Primärantikörper
  • Applikationshinweise
    ELISA. Western BLot: 2 - 4 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
  • Target
    IL23A (Interleukin 23, alpha subunit p19 (IL23A))
    Andere Bezeichnung
    Interleukin-23 alpha / IL23A (IL23A Produkte)
    Hintergrund
    Like interleukin-27 (IL-27), IL-23 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the IL-12p40 subunit and a novel p19 subunit. IL-23 is secreted by activated dendritic cells, macrophages, and monocytes. Its biological activities include enhancing the proliferation of memory T cells and the production of IFN-gamma, IL-12, and TNF-alpha from activated T cells, and can stimulate macrophages to produce TNF-alpha and nitric oxide. It has also been shown to possess potent anti-tumor and anti-metastatic activity in mouse models of cancer, suggesting a potential role for IL-23 in therapeutic treatment of cancer.Synonyms: IL-23 subunit alpha, IL-23p19, Interleukin-23 subunit p19, SGRF
    Gen-ID
    51561
    UniProt
    Q9NPF7
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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