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ILP-2 Antikörper

BIRC8 Reaktivität: Human, Ratte, Maus WB, IF, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN500020
  • Target Alle ILP-2 (BIRC8) Antikörper anzeigen
    ILP-2 (BIRC8) (Baculoviral IAP Repeat-Containing 8 (BIRC8))
    Reaktivität
    Human, Ratte, Maus
    Wirt
    • 30
    • 2
    Kaninchen
    Klonalität
    • 32
    Polyklonal
    Konjugat
    • 11
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ILP-2 Antikörper ist unkonjugiert
    Applikation
    • 13
    • 13
    • 9
    • 8
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Spezifität
    ILP-2 antibody was raised with against a synthetic peptide corresponding to amino acids near the amino terminus of human ILP-2.
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    Human ILP-2 Peptide
    Isotyp
    IgG
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    Discover our top product BIRC8 Primärantikörper
  • Applikationshinweise
    ELISA. Western Blot: 1 to 2 μg/mL. Human HepG2 or MOLT4 cell lysate can be used as a positivecontrol and a band at approximately 33 kDa can be detected. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C.
  • Target
    ILP-2 (BIRC8) (Baculoviral IAP Repeat-Containing 8 (BIRC8))
    Andere Bezeichnung
    BIRC8 / ILP2 (BIRC8 Produkte)
    Synonyme
    ILP-2 antikoerper, ILP2 antikoerper, hILP2 antikoerper, baculoviral IAP repeat containing 8 antikoerper, BIRC8 antikoerper
    Hintergrund
    Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family including IAP, XIAP/ILP-1/MIHA, and Livin/KIAP that bind to and inhibits specific proteases. A novel member in the IAP protein family was recently identified and designated ILP-2 for IAP-like protein-2 (1). ILP-2 has high homology to ILP-1, but is encoded by a distinct gene that is solely expressed in testis of tested normal human tissues (1). ILP-2, unlike ILP-1, has no inhibitory effect on Fas and TNF induced apoptosis, but potently inhibits apoptosis induced by overexpression of Bax or by coexpression of caspase-9 with Apaf-1. ILP-2 interacts with the processed caspase-9. These results suggest that ILP-2 is a novel IAP family member with restricted specificity for caspase-9.Synonyms: Baculoviral IAP repeat-containing protein 8, IAP-like protein 2, ILP-2, Inhibitor of apoptosis-like protein 2, Testis-specific inhibitor of apoptosis
    Gen-ID
    112401
    NCBI Accession
    NP_203127
    UniProt
    Q96P09
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