STRADB Antikörper (C-Term)

Produktnummer ABIN500024

Produktdetails anti-STRADB Antikörper

Target: STRADB (STE20-Related Kinase Adaptor beta (STRADB))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STRADB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: ILPIP antibody was raised against a synthetic peptide corresponding to amino acids at the C-terminus of human ILPIP.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Human ILPIP (C-Terminus) Peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: 0.5 to 2 μg/mL. Aa 34 kDa band can be detected. Anti-ILPIP is specific forhuman ILPIP only. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu STRADB

Target: STRADB (STE20-Related Kinase Adaptor beta (STRADB))

Andere Bezeichnung: STRAD beta / ILPIP (STRADB Produkte)

Hintergrund: ILPIP (ILP-interacting protein) has recently been shown to interact with XIAP, a member of the IAP (Inhibitor of Apoptosis) protein family (1). Together, these two proteins synergistically activate the TAK1/JNK1 signal transduction pathway, which acts to protect against the interleukin-1 converting enzyme of Fas-induced apotosis (1,2). This protein was independently isolated and characterized as polyploidy-associated protein kinase (PAPK), a member of the Ste20/germinal center kinase family that modulates cytoskeletal organization and cell survival (3), suggesting that its protective role may be a function of its kinase activity. Although two mRNA sequences have been isolated, only the shorter isoform has been observed.Synonyms: ALS2CR2, CALS-21, PRO1038, Pseudokinase ALS2CR2, STE20-related kinase adapter protein beta, STRADB

Gen-ID: 55437

NCBI Accession: NP_061041

UniProt: Q9C0K7

Pathways: AMPK Signaling