PDE4DIP Antikörper (AbBy Fluor® 750)

Produktnummer ABIN5000244

Produktdetails anti-PDE4DIP Antikörper (AbBy Fluor® 750)

Target: PDE4DIP (phosphodiesterase 4D Interacting Protein (PDE4DIP))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE4DIP Antikörper ist konjugiert mit AbBy Fluor® 750

Applikation: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CMYA2/PDE4DIP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu PDE4DIP

Target: PDE4DIP (phosphodiesterase 4D Interacting Protein (PDE4DIP))

Andere Bezeichnung: CMYA2 (PDE4DIP Produkte)

Hintergrund:

Synonyms: Cardiomyopathy associated protein 2, Cardiomyopathy-associated protein 2, CMYA2, MMGL, MYOME_HUMAN, Myomegalin, Pde4dip, Phosphodiesterase 4D interacting protein, Phosphodiesterase 4D-interacting protein.

Background: May function as an anchor sequestering components of the cAMP-dependent pathway to Golgi and/or centrosomes.Myomegalin, is a 2,346 amino acid protein that contains one NBPF domain and localizes to the nucleus, cytoplasm, centrosome and Golgi apparatus. Expressed at high levels in fetal and adult heart and at lower levels in brain and placenta, myomegalin is thought to function as an anchoring protein that sequesters members of the cAMP-dependent pathway to the Golgi and to centrosomes, thereby mediating cAMP pathway dynamics. Translocations in the gene that encodes myomegalin are associated with myeloproliferative disorders (MBDs), a group of diseases caused by an overproduction of blood cells. Myomegalin exists as twelve isoforms due to alternative splicing events.

Gen-ID: 9659

Pathways: SARS-CoV-2 Protein Interaktom