GARP Antikörper (AA 856-960) (AbBy Fluor® 680)
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- Target Alle GARP (CNGB1) Antikörper anzeigen
- GARP (CNGB1) (Cyclic Nucleotide Gated Channel beta 1 (CNGB1))
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Bindungsspezifität
- AA 856-960
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GARP Antikörper ist konjugiert mit AbBy Fluor® 680
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Applikation
- Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Homologie
- Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human CNGB1
- Isotyp
- IgG
- Top Product
- Discover our top product CNGB1 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- GARP (CNGB1) (Cyclic Nucleotide Gated Channel beta 1 (CNGB1))
- Andere Bezeichnung
- CNG4/GARP (CNGB1 Produkte)
- Synonyme
- CNCG2 antikoerper, CNCG3L antikoerper, CNCG4 antikoerper, CNG4 antikoerper, CNGB1B antikoerper, GAR1 antikoerper, GARP antikoerper, RCNC2 antikoerper, RCNCb antikoerper, RCNCbeta antikoerper, RP45 antikoerper, Gm1959 antikoerper, Cngb1b antikoerper, CNGB1 antikoerper, si:ch211-160j6.1 antikoerper, cyclic nucleotide gated channel beta 1 antikoerper, cyclic nucleotide gated channel beta 1a antikoerper, CNGB1 antikoerper, Cngb1 antikoerper, cngb1a antikoerper
- Hintergrund
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Synonyms: CNCG2, CNCG3L, CNCG4, CNG 4, CNG-4, CNG channel 4, CNG channel beta 1, CNG4, CNGB 1, CNGB1, CNGB1B, Cyclic nucleotide gated cation channel 4, Cyclic nucleotide gated cation channel, Cyclic nucleotide gated cation channel beta 1, Cyclic nucleotide gated cation channel gamma, Cyclic nucleotide gated cation channel modulatory subunit, Cyclic nucleotide gated channel photoreceptor cGMP gated 3 gamma like, Cyclic nucleotide gated channel beta 1, GAR1, Glutamic acid rich protein, RCNC2, RCNCb, RCNCbeta, RP45, CNGB1_HUMAN.
Background: Cyclic nucleotide-gated (CNG) cation channels are heteromeric complexes made up of principal alpha and modulatory beta subunits (1,2). The alpha subunits consist of CNG1-3 and form functional cation channels by themselves (1,2). The beta subunits consist of CNG4-6 and, unlike the alpha subunits, do not form functional channels, but rather modify the properties of channels (1,2). CNG channels are essential components of olfactory and visual transduction (1,2). In olfactory neurons, CNG2, CNG4.3 and CNG5 form Ca2+ permeable channels, which open and depolarize the cell in response to cAMP (1-3). In rod photoreceptors, CNG1 and CNG4.1 combine to form Ca ion permeable channels, which give rise to a current in response to cGMP (1-3). CNG3 and CNG6 are expressed in cone receptors and may combine to form a native cGMP-activated channel (2,3). CNG channels have been implicated in other areas (4-6). CNG1 is also expressed in medium-sized and small-sized arteries, suggesting a role for CNG in the regulation of arterial blood pressure and of blood supply to different regions (4). CNG1, CNG4.1 and CNG4.2 have been detected in the rat pineal gland (5). CNG2, CNG4.3 and CNG5 are present in GT1 cell lines and may play a role in the secretion of gonadotropin-releasing hormone (6).
- UniProt
- Q14028
- Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
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