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CRBN Antikörper (AA 210-288) (AbBy Fluor® 680)

CRBN Reaktivität: Maus, Ratte IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 680
Produktnummer ABIN5000486
  • Target Alle CRBN Antikörper anzeigen
    CRBN (Cereblon (CRBN))
    Bindungsspezifität
    • 14
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 210-288
    Reaktivität
    • 19
    • 18
    • 11
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus, Ratte
    Wirt
    • 23
    • 2
    Kaninchen
    Klonalität
    • 25
    Polyklonal
    Konjugat
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CRBN Antikörper ist konjugiert mit AbBy Fluor® 680
    Applikation
    • 12
    • 12
    • 11
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Maus, Ratte
    Homologie
    Human,Dog,Cow,Sheep,Pig,Horse,Rabbit,Zebrafish
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CRBN
    Isotyp
    IgG
    Top Product
    Discover our top product CRBN Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    CRBN (Cereblon (CRBN))
    Andere Bezeichnung
    CRBN (CRBN Produkte)
    Synonyme
    zgc:92404 antikoerper, mrt2a antikoerper, F3N11.21 antikoerper, MRT2 antikoerper, MRT2A antikoerper, 2610203G15Rik antikoerper, 2900045O07Rik antikoerper, AF229032 antikoerper, AW108261 antikoerper, piL antikoerper, cereblon antikoerper, ATP-dependent protease La (LON) domain protein antikoerper, crbn antikoerper, CRBN antikoerper, AT2G25740 antikoerper, Crbn antikoerper
    Hintergrund

    Synonyms: Cereblon, DKFZp781K0715, MGC27358, MRT2A, OTTHUMP00000209555, piL, Protein cereblon, Protein x 0001, 2610203G15Rik, 2900045O07Rik, AF229032, AW108261, CRBN_HUMAN.

    Background: CRBN is a 442 amino acid protein which is highly concentrated in human brain tissue. CRBN functions are thought to be related to energy metabolism, learning and memory. Localized to the cytoplasm, CRBN acts as a protease in mitochondria and is thought to regulate the assembly of KCNT1, as well as the surface expression of KCNT1 in brain regions known to affect memory and learning, such as the hippocampus. The gene encoding CRBN belongs to a family of ATP-dependent lon proteases that play a role in membrane trafficking and proteolysis. Defects in the CRBN gene are associated with mild mental retardation.

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