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CRIPT Antikörper (AA 21-80) (AbBy Fluor® 750)

CRIPT Reaktivität: Human WB, IF (p), IF (cc) Wirt: Kaninchen Polyclonal AbBy Fluor® 750
Produktnummer ABIN5000526
  • Target Alle CRIPT Antikörper anzeigen
    CRIPT (Cysteine-Rich PDZ-Binding Protein (CRIPT))
    Bindungsspezifität
    • 14
    • 6
    AA 21-80
    Reaktivität
    • 22
    • 1
    • 1
    Human
    Wirt
    • 21
    • 1
    Kaninchen
    Klonalität
    • 21
    • 1
    Polyklonal
    Konjugat
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CRIPT Antikörper ist konjugiert mit AbBy Fluor® 750
    Applikation
    • 17
    • 12
    • 12
    • 9
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Homologie
    Human,Mouse,Rat,Cow,Pig,Chicken
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CRIPT
    Isotyp
    IgG
    Top Product
    Discover our top product CRIPT Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    CRIPT (Cysteine-Rich PDZ-Binding Protein (CRIPT))
    Andere Bezeichnung
    CRIPT (CRIPT Produkte)
    Synonyme
    CRIPT antikoerper, hspc139 antikoerper, cript antikoerper, im:7137989 antikoerper, zgc:110618 antikoerper, 1200020A08Rik antikoerper, AA589469 antikoerper, CXXC repeat containing interactor of PDZ3 domain antikoerper, cysteine-rich PDZ-binding protein antikoerper, CXXC repeat containing interactor of PDZ3 domain S homeolog antikoerper, CRIPT antikoerper, cript antikoerper, LOC725850 antikoerper, cript.S antikoerper, Cript antikoerper
    Hintergrund

    Synonyms: CRIPT, CRIPT_HUMAN, Cysteine rich interactor of PDZ3, Cysteine rich PDZ binding protein, Cysteine-rich interactor of PDZ three, Cysteine-rich interactor of PDZ3, Cysteine-rich PDZ-binding protein, HSPC139, HSPC139 protein, Hypothetical protein CRIPT, Postsynaptic protein CRIPT.

    Background: The PSD-95/SAP 90 family of proteins, which are known to bind to and cluster various membrane proteins, are involved in the organization of synaptic structure. These proteins are physically and functionally linked to cytoskeletal and/or signaling proteins. CRIPT (for cysteine-rich interactor of PDZ three), a novel postsynaptic protein, binds specifically to the PDZ3 domain of PSD-95/SAP 90. CRIPT induces the recruitment of PSD-95/SAP 90 to microtubules, and it has been shown to bind directly to microtubules, indicating that it may be responsible for cytoskeletal anchoring of PSD-95/SAP 90. CRIPT is widely expressed outside of the brain and is highly conserved from animals to plants suggesting a wider role in regulating cytoskeleton-membrane associations.

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