CTDSPL Antikörper (AA 175-276) (AbBy Fluor® 680)

Produktnummer ABIN5000675

Produktdetails anti-CTDSPL Antikörper (AbBy Fluor® 680)

Target: CTDSPL (CTD Small Phosphatase-Like Protein (CTDSPL))

Bindungsspezifität: AA 175-276

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CTDSPL Antikörper ist konjugiert mit AbBy Fluor® 680

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus

Homologie: Rat,Cow,Sheep,Pig,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CTDSPL

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CTDSPL

Target: CTDSPL (CTD Small Phosphatase-Like Protein (CTDSPL))

Andere Bezeichnung: CTDSPL (CTDSPL Produkte)

Hintergrund:

Synonyms: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3, CTD small phosphatase-like protein, CTDSL_HUMAN, CTDSP-like, Ctdspl, hYA22, N-like protein, NLI-interacting factor 1, Nuclear LIM interactor-interacting factor 1, Protein YA22, RBSP3, SCP3, Small C-terminal domain phosphatase 3, Small CTD phosphatase 3.

Background: Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation (By similarity). Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.

Gen-ID: 10217