KDM3A Antikörper (N-Term)

Produktnummer ABIN500074

Produktdetails anti-KDM3A Antikörper

Target: KDM3A (Lysine (K)-Specific Demethylase 3A (KDM3A))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KDM3A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects KDM3A / JHDM2A. It will not cross-react with JMJD1B or JMJD1C.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Peptide affinity chromatography

Immunogen: JMJD1A antibody was raised against a 16 amino acid peptide from near the amino terminus of human JMJD1A.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu KDM3A

Target: KDM3A (Lysine (K)-Specific Demethylase 3A (KDM3A))

Andere Bezeichnung: KDM3A / JHDM2A (KDM3A Produkte)

Synonyme: JHDM2A antikoerper, JHMD2A antikoerper, JMJD1 antikoerper, JMJD1A antikoerper, TSGA antikoerper, tsga antikoerper, jmjd1 antikoerper, jhdm2a antikoerper, jhmd2a antikoerper, jmjd1a antikoerper, 1700105C21Rik antikoerper, C230043E16Rik antikoerper, JHDM2a antikoerper, Jmjd1 antikoerper, Jmjd1a antikoerper, KDM2A antikoerper, TGSA antikoerper, Tsga antikoerper, mKIAA0742 antikoerper, KDM3A antikoerper, kdm3a antikoerper, lysine demethylase 3A antikoerper, lysine (K)-specific demethylase 3A antikoerper, lysine-specific demethylase 3A antikoerper, lysine (K)-specific demethylase 3A S homeolog antikoerper, KDM3A antikoerper, kdm3a antikoerper, Kdm3a antikoerper, LOC100453519 antikoerper, kdm3a.S antikoerper

Hintergrund: The jumonji domain containing 1A protein (JMJD1A) was originally discovered as a testes specific gene, but has been found to be expressed in numerous tissues. JMJD1A is a histone demethylase and specifically demethylates mono- and dimethyl-H3K9. It has also been found to be a novel interaction partner with ER71, a transcription factor expressed in the testes of adult mice and during embryogenesis. JMJD1A is also a downstream gene of STAT3, a protein that has been found to be important in the maintenance of mouse embryonic stem (mES) cells, and decreased JMJD1A expression correlated with the differentiation of cultured mES cells following the removal of the cytokine LIF. These findings suggest that JMJD1A might be a critical signaling molecule underlying the maintenance of pluripotency in embryonic stem cells. At least two isoforms of JMJD1A are known to exist.Synonyms: JMJD1, JMJD1A, JmjC domain-containing histone demethylation protein 2A, Jumonji domain-containing protein 1A, KIAA0742, Lysine-specific demethylase 3A, TSGA

Gen-ID: 55818

NCBI Accession: NP_060903

UniProt: Q9Y4C1

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Warburg Effekt