CLEC7A Antikörper (AA 66-110) (AbBy Fluor® 750)
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- Target Alle CLEC7A Antikörper anzeigen
- CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))
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Bindungsspezifität
- AA 66-110
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CLEC7A Antikörper ist konjugiert mit AbBy Fluor® 750
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Applikation
- Flow Cytometry (FACS), Western Blotting (WB)
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Beta-glucan receptor
- Isotyp
- IgG
- Top Product
- Discover our top product CLEC7A Primärantikörper
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- Applikationshinweise
- IF(IHC-P) 1:50-200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))
- Andere Bezeichnung
- DECTIN-1/ beta Glucan Receptor (CLEC7A Produkte)
- Synonyme
- CLEC7A antikoerper, BGR antikoerper, Clecsf12 antikoerper, beta-GR antikoerper, CANDF4 antikoerper, CLECSF12 antikoerper, DECTIN1 antikoerper, Clec7b antikoerper, RGD1565140 antikoerper, C-type lectin domain containing 7A antikoerper, C-type lectin domain family 7, member a antikoerper, CLEC7A antikoerper, Clec7a antikoerper
- Hintergrund
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Synonyms: BGR, CD369, CANDF4, DECTIN1, CLECSF12, C-type lectin domain family 7 member A, Beta-glucan receptor, C-type lectin superfamily member 12, Dendritic cell-associated C-type lectin 1, DC-associated C-type lectin 1, Dectin-1, CLEC7A, UNQ539/PRO1082
Background: Lectin that functions as pattern receptor specific for beta-1,3-linked and beta-1,6-linked glucans, such as cell wall constituents from pathogenic bacteria and fungi. Necessary for the TLR2-mediated inflammatory response and for TLR2-mediated activation of NF-kappa-B. Enhances cytokine production in macrophages and dendritic cells. Mediates production of reactive oxygen species in the cell. Mediates phagocytosis of C.albicans conidia. Binds T-cells in a way that does not involve their surface glycans and plays a role in T-cell activation. Stimulates T-cell proliferation (By similarity).
- Gen-ID
- 64581
- UniProt
- Q9BXN2
- Pathways
- Activation of Innate immune Response
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