DPPA2 Antikörper (AbBy Fluor® 750)

Produktnummer ABIN5001475

Produktdetails anti-DPPA2 Antikörper (AbBy Fluor® 750)

Target: DPPA2 (Developmental Pluripotency Associated 2 (DPPA2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DPPA2 Antikörper ist konjugiert mit AbBy Fluor® 750

Applikation: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse DPPA2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu DPPA2

Target: DPPA2 (Developmental Pluripotency Associated 2 (DPPA2))

Andere Bezeichnung: DPPA2 (DPPA2 Produkte)

Synonyme: 2410088E07Rik antikoerper, C80932 antikoerper, D19Mgi18 antikoerper, ECAT15-2 antikoerper, CT100 antikoerper, PESCRG1 antikoerper, developmental pluripotency associated 2 antikoerper, ABC-type oliopeptide/dipeptide transporter, periplasmic binding protein DppA antikoerper, Dppa2 antikoerper, DPPA2 antikoerper, dppA2 antikoerper

Hintergrund:

Synonyms: Developmental Pluripotency Associated 2, developmental pluripotency associated gene2, PESCRG1, Pluripotent embryonic stem cell related protein 1, cancer/testis antigen 100, CT100, developmental pluripotency-associated gene 2, developmental pluripotency-associated protein 2, ECAT15-2, embryonic stem cell ESC associated transcript 15-2, PESCRG1, Pluripotent embryonic stem cell related protein 1, Pluripotent embryonic stem cell-related gene 1, Pluripotent embryonic stem cell-related gene 1 protein .

Background: SCRG1 (scrapie-responsive protein 1) is a 98 amino acid secreted protein that belongs to the SCRG1 family. The SCRG1 protein contains a 20-amino acid signal peptide, and is expressed abundantly in the central nervous system of human adult, but not at all in fetal brain. The protein is targeted to the Golgi apparatus and large dense-core vesicles/secretory granules in neurons. High levels of SCRG1 transcripts are also observed in testis and aorta. SCRG1 is associated with neurodegenerative changes observed in transmissible spongiform encephalopathies. It may play a role in host response to prion-associated infections. The SCRG1 protein may be partly included in the membrane or secreted by the cells due to its hydrophobic N-terminus. The human and mouse SCRG1 proteins share 83 % sequence identity. The SCRG1 gene is conserved in chimpanzee, cow, mouse, rat and chicken, and maps to human chromosome 4q34.1.

Gen-ID: 151871

Pathways: Stem Cell Maintenance