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DTX2 Antikörper (AA 331-430) (AbBy Fluor® 680)

DTX2 Reaktivität: Human WB, IF (p), IF (cc) Wirt: Kaninchen Polyclonal AbBy Fluor® 680
Produktnummer ABIN5001538
  • Target Alle DTX2 Antikörper anzeigen
    DTX2 (Deltex Homolog 2 (DTX2))
    Bindungsspezifität
    • 14
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 331-430
    Reaktivität
    • 34
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 31
    • 2
    • 1
    Kaninchen
    Klonalität
    • 34
    Polyklonal
    Konjugat
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DTX2 Antikörper ist konjugiert mit AbBy Fluor® 680
    Applikation
    • 26
    • 12
    • 12
    • 8
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Homologie
    Human,Mouse,Rat,Horse,Zebrafish
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human DTX2
    Isotyp
    IgG
    Top Product
    Discover our top product DTX2 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    DTX2 (Deltex Homolog 2 (DTX2))
    Andere Bezeichnung
    DTX2 (DTX2 Produkte)
    Synonyme
    RNF58 antikoerper, 2610524D08Rik antikoerper, AA408415 antikoerper, AU022494 antikoerper, Deltex2 antikoerper, dtx2 antikoerper, deltex E3 ubiquitin ligase 2 antikoerper, probable E3 ubiquitin-protein ligase DTX2 antikoerper, deltex 2, E3 ubiquitin ligase antikoerper, deltex 2, E3 ubiquitin ligase S homeolog antikoerper, DTX2 antikoerper, Dtx2 antikoerper, LOC735784 antikoerper, LOC747633 antikoerper, dtx2 antikoerper, dtx2.S antikoerper
    Hintergrund

    Synonyms: Deltex 2, Deltex2, hDTX2, Highly similar to hPMSR6 [H.sapiens], Protein deltex 2, RING finger protein 58, RNF58, Zinc ion binding protein, DTX2_HUMAN.

    Background: DTX2 belongs to the Deltex family. It contains one RING-type zinc finger and two WWE domains. DTX2 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. It probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context, mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. DTX2 also functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity. The WWE domains are thought to mediate some protein-protein interaction, and are frequently found in ubiquitin ligases. There are two named isoforms.

    Gen-ID
    113878
    Pathways
    Notch Signalweg
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