SCARB2 Antikörper (Center)

Produktnummer ABIN500172

Produktdetails anti-SCARB2 Antikörper

Target: SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))

Bindungsspezifität: Center

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SCARB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects SCARB2

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Peptide affinity chromatography

Immunogen: LIMP2 antibody was raised against a 16 amino acid peptide from near the center of human LIMP2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu SCARB2

Target: SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))

Andere Bezeichnung: SCARB2 (SCARB2 Produkte)

Synonyme: cd36l2 antikoerper, fi13c07 antikoerper, chunp6914 antikoerper, wu:fi13c07 antikoerper, SCARB2 antikoerper, scarb2 antikoerper, AMRF antikoerper, CD36L2 antikoerper, EPM4 antikoerper, HLGP85 antikoerper, LGP85 antikoerper, LIMP-2 antikoerper, LIMPII antikoerper, SR-BII antikoerper, 9330185J12Rik antikoerper, Cd36l2 antikoerper, MLGP85 antikoerper, LimpII antikoerper, scavenger receptor class B, member 2a antikoerper, scavenger receptor class B member 2 antikoerper, scavenger receptor class B, member 2 antikoerper, scarb2a antikoerper, SCARB2 antikoerper, scarb2 antikoerper, Scarb2 antikoerper

Hintergrund: The lysosomal integral membrane protein 2 (LIMP2) is a heavily glycosylated type III transmembrane protein, the majority of which exists in the lumen of the lysosome and a cytoplasmic domain of approximately 20 amino acids. A deficiency of LIMP2 in mice causes uretic pelvic junction obstruction, deafness, and peripheral neuropathy associated with impaired vesicular trafficking and distribution of apically expressed proteins. More recently, LIMP2 was shown to act as a receptor to bind b-glucocerebrosidase, the enzyme defective in Gaucher disease, a lysosomal storage disorder. LIMP2-deficient mice showed missorted as well as secreted b-glucocerebrosidase, suggesting that LIMP2 also functions as the mannose-6-phosphate-independent trafficking receptor. Despite its predicted molecular weight, LIMP2 runs at approximately 80 - 85 kDa in SDS-PAGE.Synonyms: 85 kDa lysosomal membrane sialoglycoprotein, CD36 antigen-like 2, CD36L2, LGP85, LIMP II, LIMP2, LIMPII, Lysosome membrane protein 2, SR-BII, SRB2, Scavenger receptor class B member 2

Gen-ID: 950

UniProt: Q14108