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MATN1 Antikörper (C-Term)

MATN1 Reaktivität: Human, Maus, Ratte WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN500238
  • Target Alle MATN1 Antikörper anzeigen
    MATN1 (Matrilin 1, Cartilage Matrix Protein (MATN1))
    Bindungsspezifität
    • 15
    • 8
    • 8
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 31
    • 21
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 42
    • 4
    Kaninchen
    Klonalität
    • 43
    • 3
    Polyklonal
    Konjugat
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MATN1 Antikörper ist unkonjugiert
    Applikation
    • 38
    • 20
    • 13
    • 13
    • 13
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects MATN1 at C-term.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, mouse, rat
    Aufreinigung
    Peptide affinity chromatography
    Immunogen
    MATN1 antibody was raised against a 13 amino acid peptide from near the carboxy terminus of human MATN1.
    Isotyp
    IgG
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  • Applikationshinweise
    ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    MATN1 (Matrilin 1, Cartilage Matrix Protein (MATN1))
    Andere Bezeichnung
    Matrilin-1 (MATN1 Produkte)
    Synonyme
    cmp antikoerper, crtm antikoerper, xmatn1 antikoerper, MGC64509 antikoerper, MGC108367 antikoerper, CMP antikoerper, CRTM antikoerper, Crtm antikoerper, Mat1 antikoerper, matrilin-1 antikoerper, matrilin 1, cartilage matrix protein L homeolog antikoerper, matrilin 1 antikoerper, matrilin 1, cartilage matrix protein antikoerper, matn1.L antikoerper, matn1 antikoerper, MATN1 antikoerper, Matn1 antikoerper
    Hintergrund
    Matrilins (MATNs) are a family of non-collagenous extra-cellular matrix (ECM) proteins consisting of four known members that have been proposed to play key roles in modulating cellular phenotypes during chondrogenesis of mesenchymal stem cells (MSCs). MATN1 and MATN3 are expressed specifically in cartilage and are among the most up-regulated ECM proteins during chondrogenesis. MATN1 is composed of two Willebrand Factor A (vWFA) domains separated by one EGF-like domain, whereas MATN3 is composed of a single N-terminal vWFA domain followed by four epidermal growth factor (EGF) repeats and a coiled-coil domain. MATN1 or MATN3 may play a role in modulating chondrogenesis during the chondrocyte differentiation process. Mutations of this gene have been associated with variety of inherited chondrodysplasias. Recent studies show that the MATN1 promoter region was associated with both susceptibility and disease progression in Adolescent idiopathic scoliosis.Synonyms: CMP, CRTM, Cartilage matrix protein, MATN1
    Gen-ID
    4146
    NCBI Accession
    NP_002370
    UniProt
    P21941
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