NDEL1 Antikörper (N-Term)

Produktnummer ABIN500391

Produktdetails anti-NDEL1 Antikörper

Target: NDEL1 (NudE Nuclear Distribution E Homolog (A. Nidulans)-Like 1 (NDEL1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NDEL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects NDEL.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse

Aufreinigung: Peptide affinity chromatpography

Immunogen: Nudel antibody was raised against a peptide corresponding to 15 amino acids near the amino terminus of human Nudel.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 0.5 - 1 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu NDEL1

Target: NDEL1 (NudE Nuclear Distribution E Homolog (A. Nidulans)-Like 1 (NDEL1))

Andere Bezeichnung: NDEL (NDEL1 Produkte)

Synonyme: EOPA antikoerper, MITAP1 antikoerper, NDE1L1 antikoerper, NDE2 antikoerper, NUDEL antikoerper, NUDE2 antikoerper, Nudel antikoerper, 2600006O07Rik antikoerper, mNudel antikoerper, wu:fi23c04 antikoerper, wu:fi23e06 antikoerper, eopa antikoerper, mitap1 antikoerper, ndel1 antikoerper, ndel1-a antikoerper, ndel1-b antikoerper, nudel antikoerper, nudE neurodevelopment protein 1 like 1 antikoerper, nudE neurodevelopment protein 1-like 1 antikoerper, nudE neurodevelopment protein 1-like 1b antikoerper, nudE neurodevelopment protein 1 like 1 L homeolog antikoerper, NDEL1 antikoerper, Ndel1 antikoerper, ndel1b antikoerper, ndel1.L antikoerper

Hintergrund: Nudel was initially discovered as a protein homologous to Aspergillus NUDE and that associated with Lis1 and polyprotein complex cytoplasmic dynein, both of which have been linked to neuronal development and migration (1,2). It was later shown to be a substrate of cdk5, a kinase known to be critical during neuronal migration, phosphorylation of Nudel by cdk5 affects its localization in neurons and affects neuritic morphology (1,3). It is thought that together with Lis1, Nudel regulates cytoplasmic dynein, a large polyprotein complex, in neuronal migration and mitosis through direct interactions (4). Similar interactions are thought to also play a role in membrane traffic in other cells as disruption of Nudel expression through RNA interference perturbed normal endomembrane flux and resulted in the fragmentation of the Golgi apparatus (3).Synonyms: EOPA, MITAP1, NUDEL, Nuclear distribution protein nudE-like 1

Gen-ID: 81565

UniProt: Q9GZM8

Pathways: Regulation of Cell Size