NUP107 Antikörper (Center)

Produktnummer ABIN500393

Der Kaninchen Polyklonal Anti-NUP107-Antikörper wurde für WB, IF und EIA validiert. Er ist geeignet, NUP107 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für NUP107 Antikörper (Center) (ABIN500393)

Target: NUP107 (Nucleoporin 107kDa (NUP107))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NUP107 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-NUP107 Antikörper

Bindungsspezifität: Center

Spezifität: This antibody detects NUP107 at center.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Peptide affinity chromatography

Immunogen: NUP107 antibody was raised against a 20 amino acid peptide from near the center of human NUP107.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 1 - 2 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu NUP107

Target: NUP107 (Nucleoporin 107kDa (NUP107))

Andere Bezeichnung: NUP107

Hintergrund: The nuclear pore complex (NPC) is a protein assembly localized at the nuclear rim and mediates macromolecular transport between the nucleus and the cytoplasm. The mammalian nucleoporin (NUP)-107 is part of the hetero-oligomeric complex that also contains NUP160, NUP133, NUP96, and mammalian homolog of yeast sec13p. While the majority of the NUP107-160 nuclear pore sub-complex localizes to the nuclear pore, a small fraction is observed at kinetochores and pro-metaphase spindle poles in mitotic cells in association with proteins such as Mad1, Mad2, Bub3 and Cdc20. Immunodepletion of the NUP107-160 complex resulted in defective spindle assembly indicating that it has multiple functions. NUP107 has recently been identified as an HIV dependency factor (HDF), suggesting that NUP107 may be an important drug target in HIV treatment. Multiple isoforms of NUP107 are known to exist.Synonyms: NUP84, Nuclear pore complex protein Nup107, Nucleoporin Nup107

Gen-ID: 57122

UniProt: P57740

Pathways: Protein targeting to Nucleus