NUP107 Antikörper (Center)

Produktnummer ABIN500393

Produktdetails anti-NUP107 Antikörper

Target: NUP107 (Nucleoporin 107kDa (NUP107))

Bindungsspezifität: Center

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NUP107 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects NUP107 at center.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Peptide affinity chromatography

Immunogen: NUP107 antibody was raised against a 20 amino acid peptide from near the center of human NUP107.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 1 - 2 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu NUP107

Target: NUP107 (Nucleoporin 107kDa (NUP107))

Andere Bezeichnung: NUP107 (NUP107 Produkte)

Synonyme: zgc:152723 antikoerper, si:dkey-27k7.3 antikoerper, Afu1g10860 antikoerper, BcDNA:LD18761 antikoerper, CG6743 antikoerper, Dmel\\CG6743 antikoerper, Nup 107 antikoerper, Nup170 antikoerper, dmNup107 antikoerper, nup107 antikoerper, SPBC582.11c antikoerper, AW541137 antikoerper, C76801 antikoerper, NUP84 antikoerper, nucleophosmin/nucleoplasmin 3 antikoerper, nucleoporin 107 antikoerper, nuclear pore complex protein Nup107 antikoerper, Nuclear pore complex protein Nup107 antikoerper, nucleoporin 107kDa S homeolog antikoerper, nucleoporin 107kDa antikoerper, Nucleoporin 107kD antikoerper, nucleoporin Nup107 antikoerper, NPM3 antikoerper, NUP107 antikoerper, nup107 antikoerper, AFUA_1G10860 antikoerper, LOC5563712 antikoerper, CpipJ_CPIJ003997 antikoerper, BDBG_00235 antikoerper, nu107 antikoerper, nup107.S antikoerper, Nup107 antikoerper

Hintergrund: The nuclear pore complex (NPC) is a protein assembly localized at the nuclear rim and mediates macromolecular transport between the nucleus and the cytoplasm. The mammalian nucleoporin (NUP)-107 is part of the hetero-oligomeric complex that also contains NUP160, NUP133, NUP96, and mammalian homolog of yeast sec13p. While the majority of the NUP107-160 nuclear pore sub-complex localizes to the nuclear pore, a small fraction is observed at kinetochores and pro-metaphase spindle poles in mitotic cells in association with proteins such as Mad1, Mad2, Bub3 and Cdc20. Immunodepletion of the NUP107-160 complex resulted in defective spindle assembly indicating that it has multiple functions. NUP107 has recently been identified as an HIV dependency factor (HDF), suggesting that NUP107 may be an important drug target in HIV treatment. Multiple isoforms of NUP107 are known to exist.Synonyms: NUP84, Nuclear pore complex protein Nup107, Nucleoporin Nup107

Gen-ID: 57122

UniProt: P57740

Pathways: Protein targeting to Nucleus