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HHCM Antikörper (AA 301-400) (AbBy Fluor® 680)

HHCM Reaktivität: Human WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 680
Produktnummer ABIN5004583
  • Target Alle HHCM Produkte
    HHCM (Mahlavu Hepatocellular Carcinoma (HHCM))
    Bindungsspezifität
    • 14
    • 11
    • 7
    • 1
    AA 301-400
    Reaktivität
    Human
    Wirt
    • 26
    Kaninchen
    Klonalität
    • 26
    Polyklonal
    Konjugat
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HHCM Antikörper ist konjugiert mit AbBy Fluor® 680
    Applikation
    • 26
    • 14
    • 12
    • 12
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human HHCM
    Isotyp
    IgG
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    HHCM (Mahlavu Hepatocellular Carcinoma (HHCM))
    Andere Bezeichnung
    HHCM (HHCM Produkte)
    Synonyme
    hhc(M) antikoerper, Mahlavu hepatocellular carcinoma antikoerper, HHCM antikoerper
    Hintergrund

    Synonyms: Hepatocellular carcinoma protein HHCM, HHCM, Mahlavu hepatocellular carcinoma, HHCM_HUMAN.

    Background: HHCM is a 467 amino acid protein that has oncogenic transforming capabilities on a variety of different cell lines. When HHCM was transfected into BRL-1 (Buffalo rat liver) or NIH3T3 cells, the cells exhibited significant morphological changes, anchorage independent growth and loss of contact inhibition. When the cells were inoculated into rats and mice, they became highly tumorigenic. HHCM gene-related DNA sequences were found in at least nineteen hepatomas of Asian origin. The gene encoding HHCM maps to human chromosome 8, which is made up of nearly 146 million bases and encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and are typically associated with a poor prognosis.

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