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HOXD9 Antikörper (AA 251-352) (AbBy Fluor® 680)

HOXD9 Reaktivität: Human WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 680
Produktnummer ABIN5004826
  • Target Alle HOXD9 Antikörper anzeigen
    HOXD9 (Homeobox D9 (HOXD9))
    Bindungsspezifität
    • 14
    • 12
    • 12
    • 7
    • 7
    • 6
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 251-352
    Reaktivität
    • 49
    • 26
    • 21
    • 9
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 61
    • 2
    Kaninchen
    Klonalität
    • 61
    • 2
    Polyklonal
    Konjugat
    • 19
    • 7
    • 7
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HOXD9 Antikörper ist konjugiert mit AbBy Fluor® 680
    Applikation
    • 51
    • 36
    • 12
    • 12
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Pig,Chicken,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human HOXD9
    Isotyp
    IgG
    Top Product
    Discover our top product HOXD9 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    HOXD9 (Homeobox D9 (HOXD9))
    Andere Bezeichnung
    HOXD9 (HOXD9 Produkte)
    Synonyme
    Hox-4.4 antikoerper, Hox-5.2 antikoerper, Xhoxd9 antikoerper, HOX4 antikoerper, HOX4C antikoerper, Hox-4.3 antikoerper, hoxd9 antikoerper, z-28 antikoerper, hoxd9a antikoerper, homeobox D9 antikoerper, homeobox D9 S homeolog antikoerper, homeo box D9 antikoerper, homeobox D9a antikoerper, Hoxd9 antikoerper, HOXD9 antikoerper, hoxd9.S antikoerper, hoxd9a antikoerper, hoxd9 antikoerper
    Hintergrund

    Synonyms: homeobox D9, Homeobox protein Hox D9, Hox 4.3, Hox 5.2, HOX4, HOX4C, RP23 313J15.10, HXD9_HUMAN.

    Background: The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes. In vivo, the HoxD9 protein interacts with the autoregulatory and cross-regulatory enhancers of the murine HoxB1 and human HoxD9 genes. Specifically, the HoxD9 protein interacts with the human control region (HCR) of the HoxD9 gene, thus inducing transcription of the HoxD9 promoter. HoxD9 may be a multifunctional transcriptional regulator, as it contains different activation domains. Activation of HoxD9 depends on the structure of the target regulatory element, and results in differential cofactor interaction. The HoxD9 protein is expressed in the early stages of mouse joint development, primarily in the articular cartilage. HoxD9 transcripts are also detected in the synovial tissue of arthritic mice, but not in that of normal mice, suggesting that HoxD9 may have a role in the pathology of arthritis. Furthermore, the HoxD9 protein is highly expressed in the synoviocytes of patients with rheumatoid arthritis (RA), but not in osteoarthritis patients. The human HoxD9 protein is also differentially expressed in the human cervical cancer cell line HeLa, but is not expressed in the normal cervix and may thus play a role in tumorigenesis.

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