PICALM Antikörper (N-Term)
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- Target Alle PICALM Antikörper anzeigen
- PICALM (Phosphatidylinositol Binding clathrin Assembly Protein (PICALM))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PICALM Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human, mouse, rat
- Aufreinigung
- Peptide affinity chromatography
- Immunogen
- PICALM antibody was raised against a 15 amino acid peptide from near the amino terminus of human PICALM.
- Isotyp
- IgG
- Top Product
- Discover our top product PICALM Primärantikörper
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- Applikationshinweise
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ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- PBS containing 0.02 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store the antibody (in aliquots) at -20 °C.
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- Target
- PICALM (Phosphatidylinositol Binding clathrin Assembly Protein (PICALM))
- Andere Bezeichnung
- PICALM (PICALM Produkte)
- Synonyme
- LAP-3 antikoerper, PEPS antikoerper, CALM antikoerper, CLTH antikoerper, LAP antikoerper, PAP180 antikoerper, fit-1 antikoerper, fit1 antikoerper, mKIAA4114 antikoerper, Calm antikoerper, leucine aminopeptidase 3 antikoerper, phosphatidylinositol binding clathrin assembly protein antikoerper, si:ch211-200p22.4 antikoerper, LAP3 antikoerper, PICALM antikoerper, Picalm antikoerper, si:ch211-200p22.4 antikoerper
- Hintergrund
- PICALM, also known as the clathrin assembly lymphoid myeloid leukemia (CALM) protein, co-localizes with clathrin at clathrin-coated areas of the plasma membrane and in the Golgi area, and is thought to be an important component of the coated pit internalization machinery. Fusion proteins involving PICALM have been implicated in acute myeloid and T-cell acute lymphoblastic leukemia. PICALM is also expressed in neurons and is present at the synapse where it facilitates the endocytosis of the synaptic vesicle protein VAMP2. Recent studies have identified variants of PICALM associated with Alzheimer's disease and have suggested this protein may play a role in the endocytosis and recycling of the amyloid protein precursor (APP).Synonyms: CALM, Clathrin assembly lymphoid myeloid leukemia protein, Phosphatidylinositol-binding clathrin assembly protein
- Gen-ID
- 8301
- NCBI Accession
- NP_009097
- UniProt
- Q13492
- Pathways
- Synaptic Membrane
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