IFI16 Antikörper (AA 201-350) (AbBy Fluor® 680)
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- Target Alle IFI16 Antikörper anzeigen
- IFI16 (Interferon, gamma-Inducible Protein 16 (IFI16))
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Bindungsspezifität
- AA 201-350
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser IFI16 Antikörper ist konjugiert mit AbBy Fluor® 680
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human IFI16
- Isotyp
- IgG
- Top Product
- Discover our top product IFI16 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- IFI16 (Interferon, gamma-Inducible Protein 16 (IFI16))
- Andere Bezeichnung
- I16/MNDA (IFI16 Produkte)
- Synonyme
- IFNGIP1 antikoerper, PYHIN2 antikoerper, IFI16 antikoerper, Ifitm3l antikoerper, Ifitml antikoerper, interferon gamma inducible protein 16 antikoerper, interferon induced transmembrane protein 2 antikoerper, myeloid cell nuclear differentiation antigen-like protein antikoerper, interferon-activable protein 203 antikoerper, IFI16 antikoerper, Ifitm2 antikoerper, LOC100156073 antikoerper, LOC488622 antikoerper, Ifi16 antikoerper
- Hintergrund
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Synonyms: Gamma-interferon-inducible protein i16, Interferon-inducible myeloid dferentiation transcriptional activator, A730048F03, D3, D3cDNA, i-d3, I16, I16B, I204, I205, i205a, i205b, NGIP1, MGC9466, Mnda, p204, PYHIN2.
Background: Interferon (IFN) Inducible 16 (IFI16) protein belongs to a family of HIN 200 human and mouse proteins. IFI16 is a nuclear protein comtaining regulatory domains such as DNA binding domain, transcriptional regulatory domain and DAPIN/PAAD domain. IFI16 has three isotypes A, B, and C (85-95 kDa), which arise as a result of mRNA alternative splicing. All are phosphorylated on serine and threonine residues and can homo and heterodimerize. Expression is restricted to the nuclei of hematopoietic cells, fibroblasts and epithelial cells. IFI16 expression in hematopoietic cells of myeloid lineage is tightly regulated and highly induced in the differentiation and proliferation of the cell. Due to its localization in the nucleus, regulation of protein expression, and ability to bind DNA, it is assumed that IFI16 has a role in transcription regulation of cell differentiation. In addition, it was found that IFI16 can act as a transcriptional repressor and is involved in regulation and activation of p53 in cancer cells.
- Gen-ID
- 3428
- Pathways
- Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Autophagie, Inflammasome
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