PROSAPIP1
Reaktivität: Maus, Ratte
WB, FACS, IF (cc), IF (p)
Wirt: Kaninchen
Polyclonal
AbBy Fluor® 350
Applikationshinweise
ELISA. Western blot: 1-2 μg/mL. Immunohistochemistry on Paraffin Sections. Recommended Positive Control. SK-N-SH Cell Lysate. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
PBS containing 0.02 % Sodium Azide as preservative
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C.
Target
ProSAPiP1 (PROSAPIP1)
(ProSAP-Interacting Protein 1 (PROSAPIP1))
PROSAPIP1 antikoerper, RP5-1187M17.10 antikoerper, Prosapip1 antikoerper, leucine zipper tumor suppressor family member 3 antikoerper, leucine zipper, putative tumor suppressor family member 3 antikoerper, LZTS3 antikoerper, Lzts3 antikoerper
Hintergrund
Prosapip1 is a binding partner of the postsynaptic density (PSD) protein ProSAP2/Shank3, a major scaffolding protein in excitatory brain synapses. Prosapip1 is thought to bind ProSAP2/Shank3 through ProSAP2/Shank3's PDZ domain and link it in turn to the Spine-associated Rap-Gap (SPAR). Prosapip1 shares significant homology with another PSD protein, PSD-Zip70, with both coding for a Fez1 domain that can be found in a total of four related protein, forming a novel family of scaffolding molecules termed 'Fezzins'. Recent studies show that Prosapip1 can be found in endocrine cells in which it is localized primarily in the hormone-storing compartment of these cells, suggesting that Prosapip1 may have other functions in non-neuronal cells.Synonyms: KIAA0552, ProSAP-interacting protein 1