ITM2C Antikörper (AA 3-88) (AbBy Fluor® 750)

Produktnummer ABIN5005630

Produktdetails anti-ITM2C Antikörper (AbBy Fluor® 750)

Target: ITM2C (Integral Membrane Protein 2C (ITM2C))

Bindungsspezifität: AA 3-88

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ITM2C Antikörper ist konjugiert mit AbBy Fluor® 750

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ITM2C

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ITM2C

Target: ITM2C (Integral Membrane Protein 2C (ITM2C))

Andere Bezeichnung: ITM2C (ITM2C Produkte)

Synonyme: 3110038L02Rik antikoerper, BRI3 antikoerper, Bricd2c antikoerper, E25 antikoerper, E25C antikoerper, ITM3 antikoerper, BRICD2C antikoerper, fj35c02 antikoerper, itm2c antikoerper, wu:fj35c02 antikoerper, zgc:66349 antikoerper, wu:fj52a04 antikoerper, zgc:92783 antikoerper, integral membrane protein 2C antikoerper, integral membrane protein 2Cb antikoerper, integral membrane protein 2Ca antikoerper, Itm2c antikoerper, ITM2C antikoerper, itm2cb antikoerper, itm2ca antikoerper

Hintergrund:

Synonyms: BRI3, BRICD2C, BRICHOS domain containing 2C, Cerebral protein 14, CT-BRI3, E25, E25C , Integral membrane protein 2C, Integral membrane protein 3, Itm2c, ITM2C_HUMAN, ITM3 antibodyNPD018, Transmembrane protein BRI3.

Background: Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation.

Gen-ID: 81618

UniProt: Q9NQX7