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KDM3B Antikörper (AA 1601-1761) (AbBy Fluor® 750)

KDM3B Reaktivität: Human, Maus, Ratte WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 750
Produktnummer ABIN5005670
  • Target Alle KDM3B Antikörper anzeigen
    KDM3B (Lysine (K)-Specific Demethylase 3B (KDM3B))
    Bindungsspezifität
    • 14
    • 8
    • 8
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1601-1761
    Reaktivität
    • 59
    • 35
    • 22
    • 7
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 60
    • 1
    Kaninchen
    Klonalität
    • 61
    Polyklonal
    Konjugat
    • 32
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KDM3B Antikörper ist konjugiert mit AbBy Fluor® 750
    Applikation
    • 47
    • 22
    • 12
    • 12
    • 7
    • 7
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Homologie
    Dog,Cow,Pig,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human JMJD1B
    Isotyp
    IgG
    Top Product
    Discover our top product KDM3B Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    KDM3B (Lysine (K)-Specific Demethylase 3B (KDM3B))
    Andere Bezeichnung
    JMJD1B (KDM3B Produkte)
    Synonyme
    KDM3B antikoerper, JMJD1B antikoerper, 5830462I21Rik antikoerper, JHDM2B antikoerper, Jmjd1b antikoerper, mKIAA1082 antikoerper, 5qNCA antikoerper, C5orf7 antikoerper, NET22 antikoerper, lysine demethylase 3B antikoerper, lysine (K)-specific demethylase 3B antikoerper, lysine-specific demethylase 3B antikoerper, KDM3B lysine (K)-specific demethylase 3B antikoerper, KDM3B antikoerper, LOC100540242 antikoerper, kdm3b antikoerper, Kdm3b antikoerper
    Hintergrund

    Synonyms: JHDM2B, JmjC domain containing histone demethylation protein 2B, JmjC domain-containing histone demethylation protein 2B , jmjd1b, Jumonji domain containing protein 1B, JUMONJI DOMAIN-CONTAINING PROTEIN 1B , KDM3B, KDM3B_HUMAN, Lysine-specic demethylase 3B, Nuclear protein 5qNCA.

    Background: JMJD1B (jumonji domain containing 1B), also known as KDM3B, 5qNCA (5q Nuclear Co-Activator) or C5orf7, is a member of the JHDM2 histone demethylase family of proteins. Expressed in a wide variety of tissues, JMJD1B localizes to the nucleus and contains one JMJC domain and a C-terminal zinc finger motif. JMJD1B functions as a histone demethylase and, using iron as a cofactor, demethylates lysine-9 of Histone H3. This suggests that JMJD1B plays a central role in the histone code. The gene encoding human JMJD1B is located within the 5q region of the genome that is often deleted in myeloid leukemias and myelodysplasias. This implies that JMJD1B may function as a tumor suppressor of myeloid leukemia. Eptopic expression of JMJD1B exhibits growth suppressive activities, further supporting a role for JMJD1B in tumor suppression.

    Gen-ID
    51780
    Pathways
    Warburg Effekt
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