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RHBDD1 Antikörper (C-Term)

RHBDD1 Reaktivität: Human, Maus WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN500589
  • Target Alle RHBDD1 Antikörper anzeigen
    RHBDD1 (Rhomboid Domain Containing 1 (RHBDD1))
    Bindungsspezifität
    • 2
    • 1
    C-Term
    Reaktivität
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 6
    Kaninchen
    Klonalität
    • 6
    Polyklonal
    Konjugat
    • 6
    Dieser RHBDD1 Antikörper ist unkonjugiert
    Applikation
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, mouse
    Aufreinigung
    Peptide affinity chromatography
    Immunogen
    RHBDD1 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human RHBDD1.
    Isotyp
    IgG
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  • Applikationshinweise
    ELISA. Western blot: 1 - 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store the antibody (in aliquots) at -20 °C.
  • Target
    RHBDD1 (Rhomboid Domain Containing 1 (RHBDD1))
    Andere Bezeichnung
    RHBDD1 (RHBDD1 Produkte)
    Synonyme
    MGC84665 antikoerper, RRP4 antikoerper, 4930418P06Rik antikoerper, mRHBDD1 antikoerper, RGD1306477 antikoerper, rRHBDD1 antikoerper, rhomboid domain containing 1 antikoerper, rhomboid domain containing 1 L homeolog antikoerper, RHBDD1 antikoerper, rhbdd1.L antikoerper, rhbdd1 antikoerper, Rhbdd1 antikoerper
    Hintergrund
    The Rhomboid family of proteins is made up of several widely conserved polytopic membrane serine proteases that play roles in growth and development. RHBDD1 is highly expressed in the testis and is involved in the cleavage of BIK, a proapoptotic member of the Bcl-2 family. Overexpression or suppression by RNAi of RHBDD1 in 293 cells will reduce or enhance BIK-mediated apoptosis, respectively, demonstrating that RHBDD1 modulates BIK-mediated apoptotic activity. In GC-1 cells, a spermatogonia cell line that can differentiate into spermatids within the seminiferous tubules, suppression of RHBDD1 expression by RNAi caused the cells to lose the ability to survive and differentiate in mouse seminiferous tubules, suggesting that RHBDD1 may be associated with mammalian spermatogenesis.Synonyms: HSD-50, HSD50, Rhomboid domain-containing protein 1
    Gen-ID
    84236
    UniProt
    Q8TEB9
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