MEX3C
Reaktivität: Human
WB, ELISA
Wirt: Kaninchen
Polyclonal
Biotin
Applikationshinweise
ELISA. Western blot. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
PBS containing 0.02 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Li, Li, Liu, Jin, Lu: "Oocyte-Specific Expression of Mouse MEX3C652AA in the Ovary and Its Potential Role in Regulating Maternal Fos mRNA." in: Biology of reproduction, Vol. 94, Issue 5, pp. 115, (2017) (PubMed).
Rkhd2 antikoerper, RKHD2 antikoerper, rkhd2 antikoerper, bm-013 antikoerper, rnf194 antikoerper, MEX-3C antikoerper, RNF194 antikoerper, A130001D14Rik antikoerper, BC035207 antikoerper, BM-013 antikoerper, mex-3 RNA binding family member C antikoerper, mex3 RNA binding family member C antikoerper, Mex3c antikoerper, MEX3C antikoerper, mex3c antikoerper
Hintergrund
Rkhd2, also known as MEX3C is a member of a novel family of four homologous human MEX3 proteins each containing two heterogeneous nuclear ribonucleoprotein K homology (KH) domains and one carboxy-terminal RING finger module. MEX3 proteins, including Rkhd2, are phosphoproteins that bind RNA through their KH domains and shuttle between the nucleus and the cytoplasm via the CRM1 export pathway. These proteins are a novel family of evolutionarily conserved RNA-binding proteins, differentially recruited to P bodies and potentially involved in post-transcriptional regulatory mechanisms. It has been suggested that genetic variations in Rkhd2 may be associated with susceptibility to essential hypertension type 8. Rkhd3 and Rkhd4, but not Rkhd2, co-localize with both the hDcp1a decapping factor and Argonaute (Ago) proteins in processing bodies (P bodies), recently characterized as centers of mRNA turnover.Synonyms: RING finger and KH domain-containing protein 2, RING finger protein 194, RNA-binding protein MEX3C, RNF194