LRRTM1 Antikörper (AA 151-250) (AbBy Fluor® 680)
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- Target Alle LRRTM1 Antikörper anzeigen
- LRRTM1 (Leucine Rich Repeat Transmembrane Neuronal 1 (LRRTM1))
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Bindungsspezifität
- AA 151-250
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser LRRTM1 Antikörper ist konjugiert mit AbBy Fluor® 680
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Pig,Chicken
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human LRRTM1
- Isotyp
- IgG
- Top Product
- Discover our top product LRRTM1 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- LRRTM1 (Leucine Rich Repeat Transmembrane Neuronal 1 (LRRTM1))
- Andere Bezeichnung
- LRRTM1 (LRRTM1 Produkte)
- Synonyme
- im:6904481 antikoerper, 4632401D06Rik antikoerper, AW125451 antikoerper, leucine rich repeat transmembrane neuronal 1 antikoerper, lrrtm1 antikoerper, LRRTM1 antikoerper, Lrrtm1 antikoerper
- Hintergrund
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Synonyms: Leucine rich repeat transmembrane neuronal 1, Leucine rich repeat transmembrane neuronal 1 protein, Leucine-rich repeat transmembrane neuronal protein 1, LRRT1_HUMAN, LRRTM1, Lrrtm1 leucine rich repeat transmembrane neuronal 1, OTTHUMP00000194829, 4632401D06Rik, AW125451, FLJ32082.
Background: The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic Alpha/Beta horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. LRRTM1 (leucine rich repeat transmembrane neuronal 1) is a 522 amino acid single-pass type I membrane protein that localizes to the endoplasmic reticulum and contains ten LRR repeats. Expressed predominately in forebrain tissue, LRRTM1 is thought to be involved in the development of forebrain structures, specifically by influencing axon trafficking, as well as neuronal differentiation and connectivity. Human LRRTM1 shares 96 % amino acid identity with its mouse counterpart, suggesting a conserved role between species. Defects in the gene encoding LRRTM1 may be associated with the pathogenesis of several common neurodevelopmental disorders.
- Pathways
- Synaptic Membrane
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