ZBTB17 Antikörper (AA 331-430) (AbBy Fluor® 750)
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- Target Alle ZBTB17 Antikörper anzeigen
- ZBTB17 (Zinc Finger and BTB Domain Containing 17 (ZBTB17))
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Bindungsspezifität
- AA 331-430
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Reaktivität
- Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ZBTB17 Antikörper ist konjugiert mit AbBy Fluor® 750
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Maus
- Homologie
- Human,Rat,Cow,Pig,Horse,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Miz1/ZNF60
- Isotyp
- IgG
- Top Product
- Discover our top product ZBTB17 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- ZBTB17 (Zinc Finger and BTB Domain Containing 17 (ZBTB17))
- Andere Bezeichnung
- Miz1/ZNF60 (ZBTB17 Produkte)
- Synonyme
- MIZ-1 antikoerper, ZNF151 antikoerper, ZNF60 antikoerper, pHZ-67 antikoerper, AA589413 antikoerper, Lp-1 antikoerper, Miz1 antikoerper, Zfp100 antikoerper, mZ13 antikoerper, Miz-1 antikoerper, zbtb17 antikoerper, zinc finger and BTB domain containing 17 antikoerper, zinc finger and BTB domain containing 17 S homeolog antikoerper, ZBTB17 antikoerper, Zbtb17 antikoerper, zbtb17.S antikoerper
- Hintergrund
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Synonyms: Miz-1, Myc-interacting zinc finger protein 1, Myc-interacting zinc finger protein, ZBT17, ZBT17_HUMAN, Zbtb17, Zinc finger and BTB domain containing protein 17, Zinc finger and BTB domain-containing protein 17, Zinc finger protein 151, Zinc finger protein 60, ZNF151, ZNF60.
Background: The Myc family, including c-Myc-, N-Myc- and L-Myc, are nuclear proteins with relatively short half lives that contribute an important role in cellular processes such as proliferation, differentiation, apoptosis and transformation. The c-Myc protein activates transcription as part of a heteromeric complex with a number of interacting partners, including Max and Mxi 1, however the transforming properties of the Myc proto-oncogene are believed to be associated with Myc-mediated transcriptional repression. A POZ domain Zn finger protein, designated Miz-1 for Myc-interacting Zn finger protein-1, is a specific target of Myc-induced gene repression. Miz-1 interacts with Myc, but not Max or other Myc partners, and binding of Myc to Miz-1 requires the helix-loop-helix domain of Myc and a short amphipathic helix located in the carboxy-terminus of Miz-1. Miz-1 associates with DNA elements on the adenovirus major late and cyclin D1 promoters and activates transcription of both promoters. Expression of Miz-1 induces potent growth arrest function, and this latency is reversed by the addition of Myc.
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, ER-Nucleus Signaling
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