MTPN Antikörper (AA 41-118) (AbBy Fluor® 750)

Produktnummer ABIN5007231

Produktdetails anti-MTPN Antikörper (AbBy Fluor® 750)

Target: MTPN (Myotrophin (MTPN))

Bindungsspezifität: AA 41-118

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MTPN Antikörper ist konjugiert mit AbBy Fluor® 750

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Myotrophin/GCDP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu MTPN

Target: MTPN (Myotrophin (MTPN))

Andere Bezeichnung: Myotrophin/GCDP (MTPN Produkte)

Synonyme: MGC76285 antikoerper, GCDP antikoerper, V-1 antikoerper, Gcdp antikoerper, wu:fa10f07 antikoerper, zgc:64078 antikoerper, 5033418D15Rik antikoerper, V1 antikoerper, myotrophin antikoerper, myotrophin S homeolog antikoerper, mtpn antikoerper, MTPN antikoerper, Mtpn antikoerper, mtpn.S antikoerper

Hintergrund:

Synonyms: FLJ31098, FLJ99857, GCDP, Granule cell dferentiation protein, MTPN, MTPN_HUMAN, Myotrophin, Protein V 1, Protein V-1, V 1, MTPN_HUMAN.

Background: Myotrophin (V-1 protein) is a ubiquitously expressed cytoplasmic protein that can translocate to the nucleus during sustained NFkB activation. The gene encoding for this protein localizes to chromosome 7q33. Myotrophin may be involved in cerebellar morphogenesis and contains an acetylated N-terminus and 2.5 internal 33 amino acid ankyrin repeats. It is important in the differentiation of cerebellar neurons, particularly of granule cells. The 117 amino acid protein has been associated with, and able to induce, cardiac hypertrophy. Myotrophin increases protooncogene, ANF and Beta-Myosin heavy chain transcript levels. Myotrophin is upregulated when myocytes undergo cyclic stretch or are treated with tumor necrosis factor Alpha (TNF Alpha) or interleukin-1Beta. Highest levels of Myotrophin are detected in brain and lowest levels in skeletal muscle.