SLITRK2 Antikörper (C-Term)

Produktnummer ABIN500754

Produktdetails anti-SLITRK2 Antikörper

Target: SLITRK2 (SLIT and NTRK-Like Family, Member 2 (SLITRK2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLITRK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects SLITRK2 C-term. It is predicted to have no cross-reactivity to other Slitrk proteins.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Peptide affinity chromatography

Immunogen: Slitrk2 antibody was raised against a 17 amino acid peptide from near the carboxy terminus of human Slitrk2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Details zu SLITRK2

Target: SLITRK2 (SLIT and NTRK-Like Family, Member 2 (SLITRK2))

Andere Bezeichnung: SLITRK2 (SLITRK2 Produkte)

Synonyme: slitrk2 antikoerper, CXorf2 antikoerper, SLITL1 antikoerper, A930040J07 antikoerper, RGD1561361 antikoerper, SLIT and NTRK-like family, member 2 antikoerper, SLIT and NTRK like family member 2 antikoerper, SLITRK2 antikoerper, slitrk2 antikoerper, Slitrk2 antikoerper

Hintergrund: SLIT and NTRK-like family 2 (Slitrk2) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the family. For example, Slitrk2 is expressed primarily in neurons in the ventricular layer of the brain. Like every other Slitrk protein except Slitrk1, overexpression of Slitrk2 inhibited neurite outgrowth in cultured neurons. Deletion analysis indicated that the functional difference between Slitrk2 and Slitrk1 is within their intracellular domains. At least two isoforms of this protein are known to exist.Synonyms: CXorf2, KIAA1854, SLIT and NTRK-like protein 2, SLITL1

Gen-ID: 84631

UniProt: Q9H156