NOB1 Antikörper (AbBy Fluor® 680)
-
- Target Alle NOB1 Antikörper anzeigen
- NOB1 (RNA-Binding Protein NOB1 (NOB1))
-
Reaktivität
- Human, Maus, Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser NOB1 Antikörper ist konjugiert mit AbBy Fluor® 680
-
Applikation
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human NOB1
- Isotyp
- IgG
- Top Product
- Discover our top product NOB1 Primärantikörper
-
-
- Applikationshinweise
- IF(IHC-P) 1:50-200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
-
- Target
- NOB1 (RNA-Binding Protein NOB1 (NOB1))
- Andere Bezeichnung
- NOB1 (NOB1 Produkte)
- Synonyme
- MEE6.26 antikoerper, MEE6_26 antikoerper, Nob1p antikoerper, fc27e05 antikoerper, si:ch73-167i17.3 antikoerper, wu:fc27e05 antikoerper, ART-4 antikoerper, MST158 antikoerper, NOB1P antikoerper, PSMD8BP1 antikoerper, 1700021I09Rik antikoerper, Psmd8bp1 antikoerper, NIN1/PSMD8 binding protein 1 homolog antikoerper, RNA-binding NOB1-like protein antikoerper, RNA-binding protein nob1 antikoerper, RNA-binding protein NOB1 antikoerper, NIN1/RPN12 binding protein 1 homolog S homeolog antikoerper, NIN1/RPN12 binding protein 1 homolog (S. cerevisiae) antikoerper, NIN1/RPN12 binding protein 1 homolog antikoerper, NOB1 antikoerper, AT5G41190 antikoerper, EDI_130960 antikoerper, CpipJ_CPIJ012739 antikoerper, BDBG_01281 antikoerper, PAAG_04204 antikoerper, PITG_13300 antikoerper, nob1.S antikoerper, nob1 antikoerper, Nob1 antikoerper
- Hintergrund
-
Synonyms: Adenocarcinoma antigen recognized by T lymphocytes 4, ART4, MST158, MSTP158, Nin one binding protein, NIN1/RPN12 binding protein 1 homolog S. cerevisiae, nob1, NOB1_HUMAN, NOB1P, Phosphorylation regulatory protein HP-10, Protein ART-4, Protein ART4, PSMD8 binding protein 1, PSMD8BP1, RNA binding protein NOB1, RNA-binding protein NOB1.
Background: NOB1P is a 412 amino acid nuclear protein that is involved in proteosome biogenesis and is required for the final step in 18S rRNA maturation. NOB1P contains a PIN domain, which functions as a nuclease in nonsense-mediated mRNA decay and is required for pre-rRNA cleavage. NOB1P interacts with Rent2, which is involved in nonsense-mediated decay of mRNAs containing premature stop codons. Expressed in placenta, spleen, endothelial cells, liver and lung, NOB1P is essential for the synthesis of 40S ribosome subunits. Supression of the gene encoding NOB1P inhibits the processing of the 20S pre-rRNA to the mature 18S rRNA, therefore leading to accumulation of high levels of 20S pre-rRNA with degradation intermediates.
- Gen-ID
- 28987
- Pathways
- Protein targeting to Nucleus
-