OAS3 Antikörper (AA 901-1000) (AbBy Fluor® 750)

Produktnummer ABIN5007972

Produktdetails anti-OAS3 Antikörper (AbBy Fluor® 750)

Target: OAS3 (2'-5' Oligoadenylate Synthetase 3 (OAS3))

Bindungsspezifität: AA 901-1000

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OAS3 Antikörper ist konjugiert mit AbBy Fluor® 750

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus

Homologie: Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human OAS3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu OAS3

Target: OAS3 (2'-5' Oligoadenylate Synthetase 3 (OAS3))

Andere Bezeichnung: OAS3 (OAS3 Produkte)

Synonyme: p100 antikoerper, Oasl10 antikoerper, 2'-5'-oligoadenylate synthetase 3 antikoerper, 2'-5' oligoadenylate synthetase 3 antikoerper, OAS3 antikoerper, Oas3 antikoerper

Hintergrund:

Synonyms: 2-5''oligoA synthase 3, 2 5' oligoA synthetase 3, 2 5'LIGO, 2 5A synthetase 3, 2''-5''-oligoadenylate synthase 3, 2-5A synthase 3, MGC133260, OAS3 2' 5' oligoadenylate synthetase 3, 100 kDa, OAS3, OAS3_HUMAN, p100, p100 OAS, p100OAS.

Background: The 2'- 5'- oligoadenylate synthetase (OAS) family is comprised of four members: OAS1, OAS2, OAS3 and OASL. These proteins are induced by interferons and function to convert ATP into 2'- 5'- linked oligomers of adenosine in the presence of double-stranded RNA and magnesium ions. Copper, iron and zinc ions strongly inhibit the OAS enzymatic activity, while manganese ions can replace magnesium ions as an activator. The OAS family plays a significant role in the inhibition of cellular protein synthesis, apoptosis and growth, and its members are important factors in viral infection resistance. OAS3, also referred to as p100, contains three adjacent OAS1-like domains and maps to the human chromosome 12q24.2

Gen-ID: 4940

Pathways: Hepatitis C